抗凝剂对酸碱及血气测定的影响。
Effects of anticoagulants on acid-base and blood gas estimations.
作者信息
Goodwin N M, Schreiber M T
出版信息
Crit Care Med. 1979 Oct;7(10):473-4. doi: 10.1097/00003246-197910000-00007.
Abstract
The use of excessive amounts of heparin to anticoagulate blood samples for pH and blood gas analysis leads to erroneously low PCO2 results, whereas pH and PO2 are relatively unaffected. Derived base deficit values accordingly will be high. Dilution is seldom less than 6% but may exceed 40%, particularly when sampling fron neonates. Sodium citrate and Heller-Paul oxalate solutions were found to be suitable alternatives to heparin, whereas EDTA was not.
摘要
使用过量肝素对用于pH和血气分析的血样进行抗凝，会导致PCO2结果错误地偏低，而pH和PO2相对不受影响。相应地，计算得出的碱缺失值会偏高。稀释度很少低于6%，但可能超过40%，尤其是从新生儿采血时。已发现柠檬酸钠和海勒 - 保罗草酸盐溶液是肝素的合适替代品，而乙二胺四乙酸（EDTA）则不是。
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