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Programmable Modular Acoustic Microrobots.

作者信息

Cherukumilli Subrahmanyam, Kirmizitas Fatma Ceren, Sokolich Max, Valencia Alejandra, Karakan M Çağatay, White Alice E, Malikopoulos Andreas A, Das Sambeeta

机构信息

Department of Mechanical Engineering, University of Delaware, Newark, DE 19716 USA.

Department of Animal and Food Sciences, University of Delaware, Newark, DE 19716 USA.

出版信息

Int Conf Manip Autom Robot Small Scales. 2023 Oct;2023. doi: 10.1109/marss58567.2023.10294125. Epub 2023 Oct 31.


DOI:10.1109/marss58567.2023.10294125
PMID:38952454
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11215786/
Abstract

Microrobots have emerged as promising tools for biomedical and in vivo applications, leveraging their untethered actuation capabilities and miniature size. Despite extensive research on diversifying multi-actuation modes for single types of robots, these tiny machines tend to have limited versatility while navigating different environments or performing specific tasks. To overcome such limitations, self-assembly microstructures with on-demand reconfiguration capabilities have gained recent attention as the future of biocompatible microrobotics, as they can address drug delivery, microsurgery, and organoid development processes. Reversible modular reconfiguration structures require specific arrangements of particles that can assume several shapes when external fields are applied. We show how magnetic interaction can be used to assemble cylindrical microrobots into modular microstructures with different shapes. The motion actuation of the formed microstructure happens due to an external acoustic field, which generates responsive forces in the air bubbles trapped in the inner cavity of the robots. An external magnetic field can also steer these structures. We illustrate these capabilities by assembling the robots into different shapes that can swim and be steered, showing the potential to perform biomedical applications. Furthermore, we confirm the biocompatibility of the cylindrical microrobot used as the building blocks of our microstructure. Exposing Chinese Hamster Ovary cells to our microrobots for 24 hours demonstrates cell viability when in contact with the microrobot.

摘要

相似文献

[1]
Programmable Modular Acoustic Microrobots.

Int Conf Manip Autom Robot Small Scales. 2023-10

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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本文引用的文献

[1]
Fabrication and open-loop control of three-lobed nonspherical Janus microrobots.

MRS Adv. 2023-11

[2]
Spatial Patterning of Micromotor Aggregation and Flux.

ChemNanoMat. 2023-8

[3]
Cellular Manipulation Using Rolling Microrobots.

Int Conf Manip Autom Robot Small Scales. 2022-7

[4]
A First-Order Approach to Model Simultaneous Control of Multiple Microrobots.

Int Conf Manip Autom Robot Small Scales. 2022-7

[5]
Role of Surface Tension in Microrobot Penetration in Membranes.

Int Conf Manip Autom Robot Small Scales. 2022-7

[6]
Doxorubicin-Loaded Microrobots for Targeted Drug Delivery and Anticancer Therapy.

Adv Healthc Mater. 2023-11

[7]
ModMag: A modular magnetic micro-robotic manipulation device.

MethodsX. 2023-4-3

[8]
Nanoparticle Assembly and Oriented Attachment: Correlating Controlling Factors to the Resulting Structures.

Chem Rev. 2023-3-22

[9]
Programmable aniso-electrodeposited modular hydrogel microrobots.

Sci Adv. 2022-12-14

[10]
Multistimuli-responsive microrobots: A comprehensive review.

Front Robot AI. 2022-11-7

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