Cherukumilli Subrahmanyam, Kirmizitas Fatma Ceren, Rivas David P, Sokolich Max, Karakan M Cagatay, White Alice E, Das Sambeeta
Department of Mechanical Engineering, University of Delaware, Newark, 19711 DE USA.
Department of Animal and Food Sciences, University of Delaware, Newark, 19711 DE USA.
J Microbio Robot. 2024;20(2):11. doi: 10.1007/s12213-024-00175-y. Epub 2024 Aug 3.
The field of microrobotics has emerged as a promising area of research with significant applications in biomedicine, both in vitro and in vivo, such as targeted cargo delivery, microsurgery, and cellular manipulation. Microrobots actuated with multiple modalities have the potential for greater adaptability, robustness, and capability to perform various tasks. Modular units that can reconfigure into various shapes, create structures that may be difficult to fabricate as one whole unit, and be assembled on-site, could provide more versatility by assembly and disassembly of units on demand. Such multi-modal modular microrobots have the potential to address challenging applications. Here, we present a biocompatible cylindrical microrobot with a dome-shaped cavity. The microrobot is actuated by both magnetic and acoustic fields and forms modular microstructures of various shapes. We demonstrate the use of these microrobots for cellular manipulation by creating patterns on a surface.
The online version contains supplementary material available at 10.1007/s12213-024-00175-y.
微型机器人技术领域已成为一个充满前景的研究领域,在生物医学的体外和体内都有重要应用,如靶向货物递送、显微手术和细胞操作。采用多种驱动方式的微型机器人具有更强的适应性、鲁棒性和执行各种任务的能力。模块化单元能够重新配置成各种形状,创建一些作为一个整体单元可能难以制造的结构,并可在现场进行组装,通过按需组装和拆卸单元可以提供更多的通用性。这种多模态模块化微型机器人有潜力解决具有挑战性的应用问题。在此,我们展示了一种带有圆顶形腔的生物相容性圆柱形微型机器人。该微型机器人由磁场和声场共同驱动,并形成各种形状的模块化微结构。我们通过在表面创建图案来演示这些微型机器人在细胞操作中的应用。
在线版本包含可在10.1007/s12213-024-00175-y获取的补充材料。