Fried A M, Loh F K, Umer M A, Dillon K P, Kryscio R
AJR Am J Roentgenol. 1985 Sep;145(3):591-4. doi: 10.2214/ajr.145.3.591.
Reports of echogenicity of the fetal lung as it relates to maturity of that organ are scant and at variance. A study was undertaken to determine if any correlation between fetal age and/or lung maturity and echogenicity could be determined in a clinical setting. Studies were performed with either linear array or mechanical sector real-time devices. Echogenicity of the fetal lung was compared with that of the fetal liver in the same longitudinal (parasagittal or coronal) sonogram. Lung echogenicity was judged to be hypodense, isodense, slightly hyperdense, or markedly hyperdense as compared with the liver texture. One hundred eighty-five studies were evaluated; of these, some 37 patients also underwent amniocentesis for determination of lecithin/sphingomyelin ratios (L/S) and presence of phosphatidyl glycerol (PG). Linear regression analyses were performed to determine if lung echogenicity would serve as an indicator of fetal maturity. No clinically applicable relation was established between fetal lung echogenicity and gestational age, L/S, or presence of PG in amniotic fluid with current methodology. The possibility persists that tissue characterization techniques may find application in such an investigation.
关于胎儿肺的回声性与其器官成熟度之间关系的报告很少且存在差异。开展了一项研究，以确定在临床环境中是否能够确定胎儿年龄和/或肺成熟度与回声性之间的任何相关性。使用线性阵列或机械扇形实时设备进行研究。在同一纵向（旁矢状面或冠状面）超声图像中，将胎儿肺的回声性与胎儿肝脏的回声性进行比较。与肝脏质地相比，肺回声性被判定为低密度、等密度、轻度高密度或明显高密度。对185项研究进行了评估；其中约37名患者还接受了羊膜穿刺术，以测定卵磷脂/鞘磷脂比值（L/S）和磷脂酰甘油（PG）的存在情况。进行线性回归分析，以确定肺回声性是否可作为胎儿成熟度的指标。采用当前方法，未在胎儿肺回声性与孕周、L/S或羊水PG存在情况之间建立临床适用的关系。组织表征技术可能会在这样的研究中得到应用，这种可能性仍然存在。
