Irede Egwonor Loveth, Awoyemi Raymond Femi, Owolabi Babatunde, Aworinde Omowunmi Rebecca, Kajola Rofiat Odunayo, Hazeez Ajibola, Raji Ayuba Adawale, Ganiyu Latifat Oluwatobi, Onukwuli Chimezie O, Onivefu Asishana Paul, Ifijen Ikhazuagbe Hilary
Department of Chemistry, Clemson University Clemson South Carolina USA.
Department of Chemistry, Mississippi State University Starkville Mississippi MS 39762 USA.
RSC Adv. 2024 Jul 3;14(29):20992-21034. doi: 10.1039/d4ra02452d. eCollection 2024 Jun 27.
This paper presents a comprehensive review of recent advancements in utilizing zinc oxide nanoparticles (ZnO NPs) to enhance antimicrobial and UV protective properties in healthcare solutions. It delves into the synthesis techniques of ZnO NPs and elucidates their antimicrobial efficacy, exploring the underlying mechanisms governing their action against a spectrum of pathogens. Factors impacting the antimicrobial performance of ZnO NPs, including size, surface characteristics, and environmental variables, are extensively analyzed. Moreover, recent studies showcasing the effectiveness of ZnO NPs against diverse pathogens are critically examined, underscoring their potential utility in combatting microbial infections. The study further investigates the UV protective capabilities of ZnO NPs, elucidating the mechanisms by which they offer UV protection and reviewing recent innovations in leveraging them for UV-blocking applications in healthcare. It also dissects the factors influencing the UV shielding performance of ZnO NPs, such as particle size, dispersion quality, and surface coatings. Additionally, the paper addresses challenges associated with integrating ZnO NPs into healthcare products and presents future perspectives for overcoming these hurdles. It emphasizes the imperative for continued research efforts and collaborative initiatives to fully harness the potential of ZnO NPs in developing advanced healthcare solutions with augmented antimicrobial and UV protective attributes. By advancing our understanding and leveraging innovative approaches, ZnO NPs hold promise for addressing pressing healthcare needs and enhancing patient care outcomes.
本文全面综述了利用氧化锌纳米颗粒(ZnO NPs)增强医疗保健解决方案中的抗菌和紫外线防护性能的最新进展。深入探讨了ZnO NPs的合成技术,阐明了其抗菌功效,探索了其对一系列病原体作用的潜在机制。广泛分析了影响ZnO NPs抗菌性能的因素,包括尺寸、表面特性和环境变量。此外,对展示ZnO NPs对多种病原体有效性的近期研究进行了批判性审查,强调了它们在对抗微生物感染方面的潜在用途。该研究进一步研究了ZnO NPs的紫外线防护能力,阐明了它们提供紫外线防护的机制,并回顾了将它们用于医疗保健领域紫外线阻挡应用的近期创新。还剖析了影响ZnO NPs紫外线屏蔽性能的因素,如粒径、分散质量和表面涂层。此外,本文还讨论了将ZnO NPs整合到医疗保健产品中所面临的挑战,并提出了克服这些障碍的未来展望。强调了持续研究努力和合作倡议的必要性,以充分利用ZnO NPs的潜力,开发具有增强抗菌和紫外线防护特性的先进医疗保健解决方案。通过增进我们的理解并利用创新方法,ZnO NPs有望满足紧迫的医疗保健需求并改善患者护理结果。