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纳米技术增强型防晒霜:平衡功效、安全性与环境影响

Nanotechnology-Enhanced Sunscreens: Balancing Efficacy, Safety, and Environmental Impact.

作者信息

Khobragade Ruchi, Chaudhary Anis Ahmad, Ali Mohamed A M, Kale Mayur, Raut Neha, Ghive Pratik, Rudayni Hassan A, Nagpurkar Krutika, Umekar Milind, Trivedi Rashmi

机构信息

Department of Quality Assurance, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee 441002, Maharashtra, India.

Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.

出版信息

Pharmaceutics. 2025 Aug 21;17(8):1080. doi: 10.3390/pharmaceutics17081080.

Abstract

Sunscreen protects skin from harmful Ultra Violet (UV) rays, preventing skin diseases like cancer and premature aging. This review explores the role of nanotechnology in enhancing sunscreen formulations by incorporating green and sustainable ingredients. Nanoparticles such as titanium dioxide and zinc oxide effectively reflect UV rays, improving protection while minimizing white residue, thereby enhancing aesthetics, stability, and efficacy. Recent advancements in formulation include lipid-based and polymer-based nanosystems that improve the delivery of active ingredients, offering multifunctional benefits. Additionally, modern sunscreens integrate anti-aging and antioxidant properties, reflecting the trend toward hybrid formulations with multiple skin benefits. The review also examines recent patents, highlighting innovations in nanotechnology-driven sunscreen formulations and delivery systems. Safety and regulatory concerns are critically analyzed, focusing on public perception of nanoparticles and their environmental impact. Issues such as manufacturing challenges and consumer hesitancy toward nano-scaled formulations due to safety considerations are also discussed. While nanotechnology presents significant potential in advancing sun protection, the review underscores the importance of balancing innovation with safety and sustainability. Ultimately, it serves as a guide for future research directions in nano-based sunscreens, advocating for responsible and informed development in the field.

摘要

防晒霜可保护皮肤免受有害紫外线(UV)的伤害,预防诸如癌症和皮肤过早衰老等皮肤疾病。本综述探讨了纳米技术在通过纳入绿色和可持续成分来增强防晒配方方面的作用。二氧化钛和氧化锌等纳米颗粒能有效反射紫外线,在减少白色残留的同时提高防护效果,从而提升美观度、稳定性和功效。配方方面的最新进展包括基于脂质和基于聚合物的纳米系统,这些系统可改善活性成分的递送,提供多种功能益处。此外,现代防晒霜还整合了抗老化和抗氧化特性,反映出朝着具有多种护肤益处的混合配方发展的趋势。该综述还研究了近期的专利,突出了纳米技术驱动的防晒配方和递送系统中的创新。对安全性和监管问题进行了批判性分析,重点关注公众对纳米颗粒的认知及其环境影响。还讨论了诸如制造挑战以及由于安全考虑消费者对纳米级配方的犹豫等问题。虽然纳米技术在推进防晒方面具有巨大潜力,但该综述强调了在创新与安全及可持续性之间取得平衡的重要性。最终,它为基于纳米的防晒霜未来的研究方向提供了指导,倡导该领域进行负责任且明智的发展。

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