Ageing, Cancer, and Disparities Research Unit, Department of Precision Health, Luxembourg Institute of Health, 1 A-B, Rue Thomas Edison, 1445, Strassen, Luxembourg.
Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, CH-8001, Zurich, Switzerland.
Curr Oncol Rep. 2024 Sep;26(9):1021-1046. doi: 10.1007/s11912-024-01567-w. Epub 2024 Jul 4.
What are the prevalence, incidence and mortality rates of cancer among individuals aged 60 or older on a national, regional, and global scale? What factors affect differences in cancer survival between older and younger adults?
The epidemiological literature on cancer in older adults, particularly in low- and middle-income countries (LMICs) and that focusing on the oldest adults, is expanding. These studies consistently show increasing global cancer incidence rates in older populations. Recent research also highlights a widening survival gap between middle-aged and older adults, with the stage at diagnosis being the primary driver. More research is needed to describe the cancer burden in older adults, especially focusing on the oldest population and LMICs, to better understand global healthcare challenges. Additionally, further exploring patient-related, clinical, and tumour-related factors which drive age-related survival differences could improve cancer outcomes in older adults.
在国家、地区和全球范围内，60 岁及以上人群的癌症患病率、发病率和死亡率是多少？哪些因素影响了老年人和年轻人之间癌症生存率的差异？
关于老年人癌症的流行病学文献，特别是在中低收入国家（LMICs）和关注最年长人群的文献正在不断增加。这些研究一致表明，老年人群的全球癌症发病率在不断增加。最近的研究还强调了中年和老年人群之间生存差距的扩大，诊断时的阶段是主要驱动因素。需要进一步研究来描述老年人的癌症负担，特别是关注最年长的人群和 LMICs，以更好地了解全球医疗保健挑战。此外，进一步探讨驱动与年龄相关的生存差异的患者相关、临床和肿瘤相关因素，可以改善老年人的癌症预后。
