Caputo O, Cattel L, Viola F
Farmaco Sci. 1979 Oct;34(10):869-75.
The bromination of 6-methyl-4-methoxy-2H-thiopyran-2-one was studied under ionic and radical conditions. The 6-bromomethyl, respectively 6-dibromomethyl derivatives were hydrolyzed to the corresponding 6-hydroxymethyl and 6-formyl derivatives. The antibacterial and antimycotic activities of the new compounds were tested.
在离子和自由基条件下研究了6-甲基-4-甲氧基-2H-硫代吡喃-2-酮的溴化反应。6-溴甲基衍生物和6-二溴甲基衍生物分别水解生成相应的6-羟甲基衍生物和6-甲酰基衍生物。对新化合物的抗菌和抗真菌活性进行了测试。