Department of Biomedical Engineering, University of Miami, Miami, FL, USA.
Bascom Palmer Eye Institute, University of Miami Health System, Miami, FL, USA.
Transl Vis Sci Technol. 2024 Jul 1;13(7):6. doi: 10.1167/tvst.13.7.6.
The purpose of this study was to validate the performance of a portable and remotely controlled slit lamp imaging adaptor.
Twenty patients with anterior eye segment conditions participated in a randomized masked clinical trial. Imaging was performed using a Haag-Streit AG, BX 900 slit lamp biomicroscope and a new slit lamp prototype. Three ophthalmologists independently reviewed masked and randomized 2D images from both instruments and conducted physical eye examinations based on these images. Inter- and intra-grader reliability were assessed using kappa statistics, and sensitivity and specificity were determined with reference to the clinical eye examinations performed during the patients' visits.
The sensitivity and specificity of the evaluations with the prototype were 47.8% and 64.1%. Similarly, the evaluations from the conventional system obtained a sensitivity and specificity of 49.5% and 66.2%. The differences in the sensitivity and specificity between imaging modalities were not statistically significant (P > 0.05). The intra-grader reliability showed moderate to substantial agreement between the systems (κ = 0.522-0.708). The inter-grader reliability also indicated moderate agreement for the evaluations with the conventional system (κ = 0.552) and the prototype (κ = 0.474).
This study presents a new prototype that exhibits diagnostic accuracy on par with conventional slit lamps and moderate reliability. Further studies with larger sample sizes are required to characterize the prototype's performance. However, its remote functionality and accessibility suggest the potential to extend eye care.
The development of portable and remotely controlled eye imaging systems will enhance teleophthalmology services and broaden access to eye care at the primary care level.
本研究旨在验证一种便携式遥控裂隙灯成像适配器的性能。
20 名患有眼前节疾病的患者参与了一项随机、单盲临床试验。采用 Haag-Streit AG、BX 900 裂隙灯生物显微镜和新型裂隙灯原型进行成像。三位眼科医生独立地对来自两种仪器的掩模和随机 2D 图像进行了审查，并根据这些图像进行了实际的眼部检查。采用 Kappa 统计评估了组内和组间的可靠性，并参考患者就诊期间进行的临床眼部检查确定了敏感性和特异性。
原型评估的敏感性和特异性分别为 47.8%和 64.1%。同样，传统系统的评估获得了 49.5%和 66.2%的敏感性和特异性。两种成像方式的敏感性和特异性差异无统计学意义（P＞0.05）。系统之间的组内可靠性显示出中度至高度一致性（κ=0.522-0.708）。组间可靠性也表明，传统系统（κ=0.552）和原型（κ=0.474）的评估具有中度一致性。
本研究提出了一种新的原型，其诊断准确性与传统裂隙灯相当，可靠性中等。需要进一步的研究来确定原型的性能。然而，其远程功能和可及性表明有可能扩展眼保健服务。
本研究旨在验证一种便携式遥控裂隙灯成像适配器的性能。
20 名患有眼前节疾病的患者参与了一项随机、单盲临床试验。采用 Haag-Streit AG、BX 900 裂隙灯生物显微镜和新型裂隙灯原型进行成像。三位眼科医生独立地对来自两种仪器的掩模和随机 2D 图像进行了审查，并根据这些图像进行了实际的眼部检查。采用 Kappa 统计评估了组内和组间的可靠性，并参考患者就诊期间进行的临床眼部检查确定了敏感性和特异性。
原型评估的敏感性和特异性分别为 47.8%和 64.1%。同样，传统系统的评估获得了 49.5%和 66.2%的敏感性和特异性。两种成像方式的敏感性和特异性差异无统计学意义（P＞0.05）。系统之间的组内可靠性显示出中度至高度一致性（κ=0.522-0.708）。组间可靠性也表明，传统系统（κ=0.552）和原型（κ=0.474）的评估具有中度一致性。
本研究提出了一种新的原型，其诊断准确性与传统裂隙灯相当，可靠性中等。需要进一步的研究来确定原型的性能。然而，其远程功能和可及性表明有可能扩展眼保健服务。
