Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati, OH, 45229, USA.
Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Pediatr Radiol. 2024 Aug;54(9):1507-1512. doi: 10.1007/s00247-024-05986-6. Epub 2024 Jul 6.
Ovarian enlargement is one of several findings of pathology, including ovarian torsion. With increasing use of MRI for acute abdominal pain in children, data for normal ovary size and appearance are needed.
To provide preliminary data on normal sizes of ovaries on MRI in pediatric patients.
This retrospective IRB-approved study included girls (5 to 17 years of age) with MRI examinations performed for indications not related to the ovaries from 2018 to 2022. For each MRI, coronal T2-weighted single shot fast spin echo and axial T2-weighted fat-saturated images were independently reviewed by three pediatric radiologists who recorded ovary visualization and ovarian linear measurements (3 planes). Ovarian volumes were calculated from linear measurements. Agreement among observers was calculated using kappa statistics and intraclass correlation coefficients.
A total of 181 MRIs were reviewed. The left ovary was visualized in 166-176 (92-97%) cases (R1-R3) and the right ovary was visualized in 165-174 (91-96%) cases with excellent agreement among reviewers (left: K = 0.89 [0.84-0.94], right: K = 0.85 [0.79-0.91]). Interrater class coefficient (ICC) for largest single dimension of the ovary was left: 0.83 (CI 0.79-0.87) and right: 0.85 (CI 0.81-0.89). There were significant moderate to strong correlations between ovarian volume and age (left: 0.67 [0.58-0.75], right: 0.66 [0.57-0.74]).
The ovaries can be adequately visualized and measured on MRI with excellent inter-reader agreement. This study serves as the foundation for developing normative values for ovarian volumes by age on MRI.
卵巢增大是病理学的发现之一，包括卵巢扭转。随着 MRI 在儿童急性腹痛中的应用越来越多，需要有关于正常卵巢大小和外观的数据。
提供儿科患者 MRI 上正常卵巢大小的初步数据。
这项回顾性 IRB 批准的研究纳入了 2018 年至 2022 年期间因与卵巢无关的适应症接受 MRI 检查的女孩（5 至 17 岁）。对于每一次 MRI，三位儿科放射科医生分别独立评估冠状 T2 加权单次快速自旋回波和轴位 T2 加权脂肪饱和图像，记录卵巢显影和卵巢线性测量值（3 个平面）。从线性测量值计算卵巢体积。观察者之间的一致性使用kappa 统计和组内相关系数来计算。
共回顾了 181 份 MRI。左卵巢在 166-176 例（92-97%）病例（R1-R3）中显示，右卵巢在 165-174 例（91-96%）病例中显示，观察者之间的一致性很好（左：K=0.89 [0.84-0.94]，右：K=0.85 [0.79-0.91]）。卵巢最大单一维度的组内相关系数（ICC）为左：0.83（CI 0.79-0.87）和右：0.85（CI 0.81-0.89）。卵巢体积与年龄之间存在显著的中度至强相关性（左：0.67 [0.58-0.75]，右：0.66 [0.57-0.74]）。
MRI 上可以充分显示和测量卵巢，并且观察者之间具有极好的一致性。本研究为 MRI 上按年龄制定卵巢体积的正常值奠定了基础。
