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转录组学:定量基因表达的方法及其在人类大脑研究中的应用。

Transcriptomics : Approaches to Quantifying Gene Expression and Their Application to Studying the Human Brain.

机构信息

Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Curr Top Behav Neurosci. 2024;68:129-176. doi: 10.1007/7854_2024_466.

Abstract

To date, the field of transcriptomics has been characterized by rapid methods development and technological advancement, with new technologies continuously rendering older ones obsolete.This chapter traces the evolution of approaches to quantifying gene expression and provides an overall view of the current state of the field of transcriptomics, its applications to the study of the human brain, and its place in the broader emerging multiomics landscape.

摘要

迄今为止,转录组学领域的特点是快速的方法开发和技术进步,新技术不断淘汰旧技术。本章追溯了定量基因表达方法的演变,并提供了转录组学领域的现状概览,包括其在人类大脑研究中的应用,以及在更广泛的新兴多组学领域中的地位。

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