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轻度认知障碍老年人的认知刺激与力量训练:一项随机对照试验

Cognitive Stimulation and Strength Training in Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial.

作者信息

Muñoz-Perete Juan Miguel, Carcelén-Fraile María Del Mar, Castellote-Caballero Yolanda, Carcelén-Fraile María Del Carmen

机构信息

Department of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.

Department of Health Sciences, Faculty of Health Sciences, University of Atlántico Medio, 35017 Las Palmas de Gran Canaria, Spain.

出版信息

Diagnostics (Basel). 2025 Jun 10;15(12):1477. doi: 10.3390/diagnostics15121477.

Abstract

The global increase in life expectancy has led to a higher prevalence of cognitive and physical decline in older adults, particularly in those with mild cognitive impairment (MCI). This study aimed to evaluate the effects of a combined cognitive stimulation and resistance training intervention on cognitive performance, physical function, and fall risk in older adults with MCI. : A randomized controlled trial was conducted with 80 community-dwelling older adults diagnosed with MCI. Participants were randomly assigned to an experimental group (EG), which received a 12-week intervention consisting of cognitive stimulation and progressive strength training, or a control group (CG), which maintained their usual routine. Pre- and post-intervention assessments included measures of cognitive function, verbal fluency, attention, processing speed, executive function, gait, balance, fall risk, and lower- and upper-body strength. : The EG showed significant improvements compared with the CG in cognitive impairment, verbal fluency, processing speed, balance, gait, and risk of falls (all < 0.05), with effect sizes ranging from moderate to large. Notably, strength gains were observed in both lower body and grip strength. Attention and executive function also improved in the EG, although with smaller effect sizes. No adverse events were reported. : A combined intervention of cognitive stimulation and resistance training is effective in improving multiple domains of cognitive and physical function in older adults with MCI. These findings support the integration of multidomain interventions in clinical and community settings to promote autonomy, reduce fall risk, and delay cognitive and functional decline. Future studies should explore the long-term sustainability of these effects and the individual contribution of each intervention component.

摘要

全球预期寿命的增加导致老年人认知和身体机能衰退的患病率更高,尤其是那些患有轻度认知障碍(MCI)的老年人。本研究旨在评估认知刺激与抗阻训练相结合的干预措施对患有MCI的老年人的认知表现、身体功能和跌倒风险的影响。:对80名被诊断患有MCI的社区居住老年人进行了一项随机对照试验。参与者被随机分配到实验组(EG),接受为期12周的包括认知刺激和渐进性力量训练的干预,或对照组(CG),保持其日常习惯。干预前后的评估包括认知功能、语言流畅性、注意力、处理速度、执行功能、步态、平衡、跌倒风险以及上下肢力量的测量。:与CG相比,EG在认知障碍、语言流畅性、处理速度、平衡、步态和跌倒风险方面有显著改善(均P<0.05),效应大小从中度到较大。值得注意的是,下肢力量和握力均有所增加。EG组的注意力和执行功能也有所改善,尽管效应大小较小。未报告不良事件。:认知刺激与抗阻训练相结合的干预措施对改善患有MCI的老年人认知和身体功能的多个领域有效。这些发现支持在临床和社区环境中整合多领域干预措施,以促进自主性、降低跌倒风险并延缓认知和功能衰退。未来的研究应探索这些效果的长期可持续性以及各干预组成部分的个体贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/12191835/9b82dd2a6666/diagnostics-15-01477-g001.jpg

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