Molnupiravir in Combination With Nirmatrelvir/Ritonavir: No Cause for Alarm.
作者信息
Kuritzkes Daniel R
机构信息
Division of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
出版信息
J Infect Dis. 2024 Dec 16;230(6):1297-1298. doi: 10.1093/infdis/jiae214.
Abstract
摘要
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本文引用的文献
1
Combined Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 Reduces Molnupiravir-Induced Mutagenicity and Prevents Selection for Nirmatrelvir/Ritonavir Resistance Mutations.严重急性呼吸综合征冠状病毒2的联合治疗可降低莫努匹拉韦诱导的致突变性并防止对奈玛特韦/利托那韦耐药突变的选择。
J Infect Dis. 2024 Dec 16;230(6):1380-1383. doi: 10.1093/infdis/jiae213.
2
SARS-CoV-2 Virologic Rebound With Nirmatrelvir-Ritonavir Therapy : An Observational Study.SARS-CoV-2 病毒学反弹与奈玛特韦-利托那韦治疗：一项观察性研究。
Ann Intern Med. 2023 Dec;176(12):1577-1585. doi: 10.7326/M23-1756. Epub 2023 Nov 14.
3
Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques.联合使用莫努匹韦-奈玛特韦能提高对食蟹猴体内 SARS-CoV-2 的抑制效果。
JCI Insight. 2023 Feb 22;8(4):e166485. doi: 10.1172/jci.insight.166485.
4
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir.SARS-CoV-2 对奈玛特韦产生耐药性的多种途径。
Nature. 2023 Jan;613(7944):558-564. doi: 10.1038/s41586-022-05514-2. Epub 2022 Nov 9.
5
Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients.莫努匹韦片用于非住院 COVID-19 患者的口服治疗。
N Engl J Med. 2022 Feb 10;386(6):509-520. doi: 10.1056/NEJMoa2116044. Epub 2021 Dec 16.
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