Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA.
Department of Medicine (Division of Cardiovascular Medicine), Stanford University, Stanford, CA 94305, USA.
Dis Model Mech. 2024 Jul 1;17(7). doi: 10.1242/dmm.050947. Epub 2024 Jul 8.
Human stem cell-based modeling systems are valuable tools that can greatly improve the clinical translation of basic research. Importantly, the successful application of human stem cell-based models to biomedical research depends on the widespread adoption of ethical principles and practical standards. To achieve this outcome, the International Society for Stem Cell Research (ISSCR) provides a comprehensive set of recommendations that aim to promote the ethical usage of human stem cells and to ensure rigor and reproducibility within the field. Understanding and implementing these recommendations should be a top priority for investigators around the world.
基于人类干细胞的建模系统是一种非常有价值的工具，可以极大地促进基础研究向临床转化。重要的是，成功地将基于人类干细胞的模型应用于生物医学研究取决于广泛采用伦理原则和实际标准。为了实现这一目标，国际干细胞研究学会（ISSCR）提供了一整套建议，旨在促进人类干细胞的伦理使用，并确保该领域的严谨性和可重复性。世界各地的研究人员都应该优先理解和实施这些建议。
