人类胚胎研究、干细胞衍生胚胎模型和体外配子发生：导致 ISSCR 指南修订的考虑因素。
Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.
机构信息
University of California, Los Angeles, CA, USA.
The Rockefeller University, New York, NY, USA.
出版信息
Stem Cell Reports. 2021 Jun 8;16(6):1416-1424. doi: 10.1016/j.stemcr.2021.05.008. Epub 2021 May 27.
Abstract
The ISSCR Guidelines for Stem Cell Research and Clinical Translation were last revised in 2016. Since then, rapid progress has been made in research areas related to in vitro culture of human embryos, creation of stem cell-based embryo models, and in vitro gametogenesis. Therefore, a working group of international experts was convened to review the oversight process and provide an update to the guidelines. This report captures the discussion and summarizes the major recommendations made by this working group, with a specific emphasis on updating the categories of review and engagement with the specialized scientific and ethical oversight process.
摘要
国际干细胞研究学会（ISSCR）的干细胞研究和临床转化指南于 2016 年进行了最后一次修订。此后，与体外培养人类胚胎、基于干细胞的胚胎模型的创建以及体外配子发生等相关的研究领域取得了快速进展。因此，召集了一个国际专家组来审查监督程序，并对指南进行更新。本报告记录了讨论内容，并总结了该工作组提出的主要建议，特别强调了更新审查类别以及与专门的科学和伦理监督程序的参与。
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