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Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines.制定全球干细胞研究和临床转化标准:2016 年 ISSCR 指南。
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本文引用的文献

1
ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts.ISCR 人类多能干细胞及其直接衍生细胞向动物宿主转移的指导原则。
Stem Cell Reports. 2021 Jun 8;16(6):1409-1415. doi: 10.1016/j.stemcr.2021.05.005. Epub 2021 May 27.
2
Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.人类胚胎研究、干细胞衍生胚胎模型和体外配子发生:导致 ISSCR 指南修订的考虑因素。
Stem Cell Reports. 2021 Jun 8;16(6):1416-1424. doi: 10.1016/j.stemcr.2021.05.008. Epub 2021 May 27.
3
Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.人源扩展多能干细胞对体外猴胚胎的嵌合贡献。
Cell. 2021 Apr 15;184(8):2020-2032.e14. doi: 10.1016/j.cell.2021.03.020.
4
Human embryo research beyond the primitive streak.超过原条期的人类胚胎研究。
Science. 2021 Mar 5;371(6533):998-1000. doi: 10.1126/science.abf3751.
5
Rethinking Human Embryo Research Policies.重新思考人类胚胎研究政策。
Hastings Cent Rep. 2021 Jan;51(1):47-51. doi: 10.1002/hast.1215.
6
The time has come to extend the 14-day limit.延长14天期限的时候到了。
J Med Ethics. 2021 Feb 2. doi: 10.1136/medethics-2020-106406.
7
Adapting the 14-day rule for embryo research to encompass evolving technologies.调整胚胎研究的14天规则以涵盖不断发展的技术。
Reprod Biomed Soc Online. 2020 Jan 21;10:1-9. doi: 10.1016/j.rbms.2019.12.002. eCollection 2020 Jun.
8
The promise and challenge of therapeutic genome editing.治疗性基因组编辑的前景与挑战。
Nature. 2020 Feb;578(7794):229-236. doi: 10.1038/s41586-020-1978-5. Epub 2020 Feb 12.
9
In vitro culture of cynomolgus monkey embryos beyond early gastrulation.食蟹猴胚胎体外培养至原肠胚后期。
Science. 2019 Nov 15;366(6467). doi: 10.1126/science.aax7890. Epub 2019 Oct 31.
10
Dissecting primate early post-implantation development using long-term in vitro embryo culture.利用长期体外胚胎培养技术解析灵长类动物早期胚胎植入后的发育过程。
Science. 2019 Nov 15;366(6467). doi: 10.1126/science.aaw5754. Epub 2019 Oct 31.

国际干细胞研究学会干细胞研究与临床转化指南:2021 年更新版。

ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.

机构信息

Francis Crick Institute, London, UK.

International Society for Stem Cell Research, Skokie, IL, USA.

出版信息

Stem Cell Reports. 2021 Jun 8;16(6):1398-1408. doi: 10.1016/j.stemcr.2021.05.012. Epub 2021 May 27.

DOI:10.1016/j.stemcr.2021.05.012
PMID:34048692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8190668/
Abstract

The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy issues that have arisen since the last update in 2016. While growing to encompass the evolving science, clinical applications of stem cells, and the increasingly complex implications of stem cell research for society, the basic principles underlying the Guidelines remain unchanged, and they will continue to serve as the standard for the field and as a resource for scientists, regulators, funders, physicians, and members of the public, including patients. A summary of the key updates and issues is presented here.

摘要

国际干细胞研究学会更新了其《干细胞研究与临床转化指南》,以应对自 2016 年上次更新以来干细胞科学及其他相关领域的进展,以及随之产生的与伦理、社会和政策相关的问题。虽然指南的范围扩大到了不断发展的科学、干细胞的临床应用,以及干细胞研究对社会日益复杂的影响,但指南所依据的基本原则保持不变,它将继续作为该领域的标准,并为科学家、监管机构、资助者、医生和包括患者在内的公众提供资源。这里介绍了主要更新和问题的摘要。