Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA.
Department of Bioethics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Stem Cell Reports. 2016 Jun 14;6(6):787-797. doi: 10.1016/j.stemcr.2016.05.001. Epub 2016 May 12.
The International Society for Stem Cell Research (ISSCR) presents its 2016 Guidelines for Stem Cell Research and Clinical Translation (ISSCR, 2016). The 2016 guidelines reflect the revision and extension of two past sets of guidelines (ISSCR, 2006; ISSCR, 2008) to address new and emerging areas of stem cell discovery and application and evolving ethical, social, and policy challenges. These guidelines provide an integrated set of principles and best practices to drive progress in basic, translational, and clinical research. The guidelines demand rigor, oversight, and transparency in all aspects of practice, providing confidence to practitioners and public alike that stem cell science can proceed efficiently and remain responsive to public and patient interests. Here, we highlight key elements and recommendations in the guidelines and summarize the recommendations and deliberations behind them.
国际干细胞研究学会（ISSCR）发布了其 2016 年干细胞研究和临床转化指南（ISSCR，2016 年）。2016 年的指南反映了对过去两版指南（ISSCR，2006 年；ISSCR，2008 年）的修订和扩展，以应对干细胞发现和应用的新领域和新兴领域，以及不断变化的伦理、社会和政策挑战。这些指南提供了一套综合的原则和最佳实践，以推动基础、转化和临床研究的进展。这些指南要求在实践的各个方面都要有严谨性、监督和透明度，使从业者和公众都有信心相信干细胞科学能够高效推进，并始终响应公众和患者的利益。在这里，我们重点介绍指南中的关键要素和建议，并总结背后的建议和审议过程。
