Onder Halil, Cetin Beyza Nur, Comoglu Selcuk
Neurology Clinic, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Türkiye.
Asian J Neurosurg. 2024 Jun 10;19(2):277-279. doi: 10.1055/s-0043-1771319. eCollection 2024 Jun.
Herein, we present the case of a 57-year-old male patient who was admitted to our center due to progressive writing difficulty and slowness of his right hand over the last 3 years. In conclusion of the clinical and laboratory workup, a diagnosis of multiple system atrophy (MSA) was established. Our report on progressive micrographia (PM) constitutes a crucial sample remarking on this intriguing manifestation in another disease subtype of MSA, which differs from Parkinson's disease in terms of the clinical and pathophysiological processes. We think that further studies are warranted to clarify the significance of this entity in movement disorder in clinical practice and to reveal the underlying neural mechanisms.
在此，我们报告一例57岁男性患者，该患者因过去3年逐渐出现书写困难和右手活动迟缓而入住我院。综合临床和实验室检查结果，确诊为多系统萎缩（MSA）。我们关于进行性小写症（PM）的报告构成了一个关键样本，说明了MSA另一种疾病亚型中的这一有趣表现，其在临床和病理生理过程方面与帕金森病不同。我们认为有必要进行进一步研究，以阐明该实体在临床实践中运动障碍中的意义，并揭示其潜在的神经机制。
