一名年轻成年人颈椎嗜酸性肉芽肿：一例罕见病例报告。
Eosinophilic granuloma of the cervical spine in a young adult: A rare case report.
作者信息
Prasad G Lakshmi, Krishna Gopal, Kale Ameya, Rajeshwari Madhu, Kale Shashank Sharad
机构信息
Department of Neurosurgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Department of Neurosurgery, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
出版信息
Surg Neurol Int. 2024 Jun 14;15:198. doi: 10.25259/SNI_262_2024. eCollection 2024.
BACKGROUND
Spinal eosinophilic granulomas (EG) are rare tumors, mostly reported in the pediatric age group. They constitute <1% of primary bone neoplasms, and cervical spine involvement is uncommon.
CASE DESCRIPTION
A 20-year-old male presented with neck pain for a 4-month duration. Six years previously, he had received six cycles of vinblastine for biopsy-proven histiocytosis of an axillary lymph node; this resulted in incomplete remission. Present magnetic resonance/computed tomography (CT) imaging revealed a lytic C2 body lesion with atlantoaxial instability. When the CT-guided biopsy was suggestive of EG, he was managed with definitive surgery and adjuvant radiotherapy.
CONCLUSION
Cervical spine EG is rare in adults. CT-guided biopsy should confirm the diagnosis and should be followed by definitive surgery and adjuvant radiotherapy.
背景
脊柱嗜酸性肉芽肿（EG）是罕见肿瘤，大多报道于儿童年龄组。它们占原发性骨肿瘤的比例不到1%，颈椎受累情况并不常见。
病例描述
一名20岁男性出现颈部疼痛4个月。6年前，他因经活检证实的腋窝淋巴结组织细胞增多症接受了6个周期的长春碱治疗；这导致病情未完全缓解。目前的磁共振成像/计算机断层扫描（CT）显示C2椎体溶骨性病变伴寰枢椎不稳。当CT引导下活检提示为EG时，对其进行了确定性手术和辅助放疗。
结论
颈椎EG在成人中罕见。CT引导下活检应确诊，随后进行确定性手术和辅助放疗。
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