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肿瘤加速生长:详述肝细胞癌的侵袭性病程

Tumor Growth in Overdrive: Detailing an Aggressive Course of Hepatocellular Carcinoma.

作者信息

Singh Simardeep, Delungahawatta Thilini, Wolff Marcos, Haas Christopher J

机构信息

MedStar Union Memorial Hospital, Baltimore, MD, USA.

MedStar Franklin Square Medical Center, Baltimore, MD, USA.

出版信息

Case Reports Hepatol. 2024 Jun 15;2024:4950398. doi: 10.1155/2024/4950398. eCollection 2024.

Abstract

Hepatocellular carcinoma ranks as the third leading cause of cancer-related mortality globally. We present a case of a rapidly progressive hepatocellular carcinoma in an 81-year-old female with metabolic abnormalities. The patient initially presented with non-specific signs and symptoms and was managed for sepsis of suspected urinary source. Unresolving laboratory markers led to repeat abdominal imaging demonstrating new hepatic lesions within six days. Biopsy confirmed moderately differentiated hepatocellular carcinoma. The patient received conservative inpatient treatment with recommendation for nutritional and performance status optimization prior to oncologic therapies, however continued to decline and passed away three months later.

摘要

肝细胞癌是全球癌症相关死亡的第三大主要原因。我们报告一例81岁患有代谢异常的女性快速进展性肝细胞癌病例。患者最初表现为非特异性体征和症状,因疑似泌尿道来源的败血症接受治疗。实验室指标持续异常导致在六天内重复进行腹部影像学检查,发现新的肝脏病变。活检证实为中度分化肝细胞癌。患者接受了保守的住院治疗,并建议在进行肿瘤治疗前优化营养和身体状况,但病情仍持续恶化,三个月后去世。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8a/11226333/39ccad743836/CRIHEP2024-4950398.001.jpg

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