Department of Allergy, Tokyo Metropolitan Children Medical Center, Musashidai Fuchu, Tokyo, 183-8561, Japan.
Curr Allergy Asthma Rep. 2024 Sep;24(9):549-557. doi: 10.1007/s11882-024-01166-6. Epub 2024 Jul 8.
Buckwheat (BW) allergy is a significant issue in Asia. This review delves into three types of BW allergy: immediate food allergy; food-dependent, exercise-induced anaphylaxis (FDEIA) as a subset of immediate food allergy; and food protein-induced enterocolitis syndrome (FPIES); by comparing data from Asian and non-Asian countries.
Most studies on BW have been published in Japan and Korea, and only a few studies on the topic have been done outside Asia. To date, seven components of common BW (Fagopyrum esculentum) and four components of Tartary BW (Fagopyrum tartaricum) have been implicated in BW allergy. Although BW-sIgE has limited utility for evaluating immediate BW allergy, Fag e 3-specific IgE, one of the components of common BW, and the skin prick test are diagnostically useful. The present review aims to shed light on the current state of knowledge, highlight research gaps, and suggest future directions in the management and understanding of BW allergy.
荞麦（BW）过敏是亚洲的一个重要问题。本综述深入探讨了三种类型的 BW 过敏：速发型食物过敏；作为速发型食物过敏亚类的食物依赖、运动诱发的过敏反应（FDEIA）；食物蛋白诱导的小肠结肠炎综合征（FPIES）；通过比较来自亚洲和非亚洲国家的数据。
大多数关于 BW 的研究都发表在日本和韩国，而亚洲以外的该主题研究很少。迄今为止，已发现普通 BW（荞麦）的七种成分和 Tartary BW（鞑靼荞麦）的四种成分与 BW 过敏有关。尽管 BW-sIgE 对评估速发型 BW 过敏的作用有限，但普通 BW 的一种成分 Fag e 3 特异性 IgE 和皮肤点刺试验具有诊断意义。本综述旨在阐明目前的知识状况，突出研究空白，并为 BW 过敏的管理和理解提出未来的方向。
