Zhang Shengcan, Liu Fang, He Jingwei
College of Materials Science and Engineering, South China University of Technology, China.
Biomater Investig Dent. 2023 Nov 18;10(1):2281090. doi: 10.1080/26415275.2023.2281090. eCollection 2023.
With the purpose of further reducing surface free energy to achieve better anti-bacterial adhesion effect of fluorinated dimethacrylate (FDMA)/tricyclo (5.2.1.0) decanedimethanol diacrylate (SR833s) based dental resin composites (DS), 1H,1H-heptafluorobutyl methacrylate (FBMA) was used to partially replace SR933s as reactive diluent. According to the degree of substitution, the obtained resin composites were marked as DSF-1 (20 wt.% of SR833s was replaced by FBMA), DSF-2 (40 wt.% of SR833s was replaced by FBMA), and DSF-3 (60 wt.% of SR833s was replaced by FBMA). Bisphenol A glycidyl dimethacrylate (Bis-GMA)/triethylene glycol dimethacrylate (TEGDMA) based resin composite (BT) was used as control. The influence of FBMA concentration on double bond conversion (DC), contact angle, surface free energy, anti-bacterial adhesion effect against (), volumetric shrinkage (VS) and shrinkage stress (SS), flexural strength (FS) and modulus (FM), water sorption (WS) and solubility (SL) were investigated. The results showed that FBMA addition could reduce surface free energy from 44.6 mN/m for DS to 32.9 mN/m for DSF-3, and lead to better anti-bacterial adhesion effect (the amounts of adherent bacteria decreased from 2.03 × 10 CFU/mm for DS to 6.44 × 10 CFU/mm for DSF-3). The FBMA had no negative effects on DC, VS, SS, WS, and SL. Too high a concentration of FBMA reduced FS and FM before water immersion, but the values were still higher than those of BT.
为了进一步降低表面自由能，以实现基于甲基丙烯酸氟化二甲基丙烯酸酯（FDMA）/三环（5.2.1.0）癸烷二甲醇二丙烯酸酯（SR833s）的牙科树脂复合材料（DS）具有更好的抗菌粘附效果，使用甲基丙烯酸1H,1H - 七氟丁酯（FBMA）部分替代SR933s作为活性稀释剂。根据取代程度，将所得树脂复合材料标记为DSF - 1（20 wt.%的SR833s被FBMA取代）、DSF - 2（40 wt.%的SR833s被FBMA取代）和DSF - 3（60 wt.%的SR833s被FBMA取代）。以双酚A二甲基丙烯酸缩水甘油酯（Bis - GMA）/三乙二醇二甲基丙烯酸酯（TEGDMA）为基础的树脂复合材料（BT）用作对照。研究了FBMA浓度对双键转化率（DC）、接触角、表面自由能、对（此处原文缺失具体细菌名称）的抗菌粘附效果、体积收缩率（VS）和收缩应力（SS）、弯曲强度（FS）和模量（FM）、吸水率（WS）和溶解度（SL）的影响。结果表明，添加FBMA可使表面自由能从DS的44.6 mN/m降至DSF - 3的32.9 mN/m，并导致更好的抗菌粘附效果（粘附细菌数量从DS的2.03×10 CFU/mm降至DSF - 3的6.44×10 CFU/mm）。FBMA对DC、VS、SS、WS和SL没有负面影响。过高浓度的FBMA会降低水浸泡前的FS和FM，但这些值仍高于BT的相应值。
