Belsheim J, Gnarpe H, Helleberg A, Svensson A
Infection. 1979;7 Suppl 4:S411-3. doi: 10.1007/BF01639024.
Co-trimazine, a new preparation of sulphadiazine and trimethoprim, was compared with nitrofurantoin in a double-blind trial on patients with acute urinary tract infections. Co-trimazine had a bacteriological cure rate of 95% as compared to 88% for nitrofurantoin. There were no statistically significant differences in laboratory findings or in clinical side-effects between the two laboratory findings or in clinical side-effects between the two preparations. It was concluded that co-trimazine might constitute a valuable addition amongst drugs suitable for treatment of acute urinary tract infections.
复方磺胺甲恶唑，一种磺胺嘧啶和甲氧苄啶的新制剂，在一项针对急性尿路感染患者的双盲试验中与呋喃妥因进行了比较。复方磺胺甲恶唑的细菌学治愈率为95%，而呋喃妥因的治愈率为88%。两种制剂在实验室检查结果或临床副作用方面均无统计学上的显著差异。得出的结论是，复方磺胺甲恶唑可能是适用于治疗急性尿路感染的药物中的一种有价值的补充药物。
