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[急性辐射损伤后期大鼠的红细胞系统状态]

[State of the erythron in rats at late periods following acute radiation injury].

作者信息

Perminova O A

出版信息

Radiobiologiia. 1985 Jul-Aug;25(4):539-44.

PMID:3898209
Abstract

During 12 months following whole-body single exposure to ionizing radiation of 6 Gy, the experimental rats did not develop anemia but exhibited appreciable morphofunctional changes in circulating erythrocytes, for instance, shortening of their half-life time and increase in a mean diameter and dry mass. In the bone marrow, the total number of erythroid elements and the index of erythronormoblasts labelled with 3H-thymidine were increased and the time of generation of these cells reduced due to shortening of the presynthetic period.

摘要

在全身单次暴露于6 Gy电离辐射后的12个月里,实验大鼠未出现贫血,但循环红细胞出现了明显的形态功能变化,例如,其半衰期缩短,平均直径和干质量增加。在骨髓中,红系细胞总数和用³H-胸腺嘧啶核苷标记的幼红细胞指数增加,且由于合成前期缩短,这些细胞的生成时间减少。

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