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[奴夫卡因对肠型放射病临床表现的改善作用]

[The modifying effect of novocaine on the clinical manifestations of the intestinal form of radiation sickness].

作者信息

Kostesha N Ia, Kuptsov V P

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1991(9):34-9.

PMID:1751616
Abstract

On rats and dogs exposed to absolute lethal doses of X-irradiation (rats--10, 12 Gy; dogs--15 Gy sublethally) it has been shown that novocaini injection to animals immediately after radiation exposure reduces the primary radiation reaction and at the same time shifts the changes in morphofunctional state of peripheric blood on 24 hours, reduces the symptoms of acute radiation sickness, increases the average life length of the animals on 1,5 days. A conclusion concerning the expressed therapeutic influence of intraperitoneal novocaini injection immediately after radiation has been drawn.

摘要

在暴露于绝对致死剂量X射线照射的大鼠和狗身上(大鼠——10、12 Gy;狗——15 Gy亚致死剂量),已表明在辐射暴露后立即给动物注射奴夫卡因可减轻初期辐射反应,同时使外周血形态功能状态的变化在24小时时发生改变,减轻急性放射病症状,使动物平均寿命延长1.5天。得出了关于辐射后立即腹腔注射奴夫卡因具有显著治疗作用的结论。

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