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病例报告:局部及全身免疫抑制后发生的巨细胞病毒性视网膜炎。

Case report: CMV retinitis following local and systemic immunosuppression.

作者信息

Menke Bryant A, Wagner William, Song Helen, Thomas William, Almeida Natalia E Castillo, Conrady Christopher D, Yeh Steven

机构信息

Department of Ophthalmology, Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United States.

Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, OH, United States.

出版信息

Front Ophthalmol (Lausanne). 2024 Mar 6;4:1354104. doi: 10.3389/fopht.2024.1354104. eCollection 2024.

Abstract

We report the case of a 71-year-old man who presented 2 years following renal transplantation with diffuse, unilateral cytomegalovirus retinitis five weeks after receiving an intravitreal dexamethasone implant device for the management of central retinal vein occlusion. Examination of the left eye showed diffuse retinal hemorrhages, attenuated and tortuous retinal vessels, and superior retinal whitening. The patient was successfully treated with serial intravitreal foscarnet injections and oral valganciclovir with disease regression observed by 12 weeks after presentation. The patient's visual acuity and examination remained stable at 9-months follow-up.

摘要

我们报告了一例71岁男性患者的病例,该患者在肾移植术后2年,因视网膜中央静脉阻塞接受玻璃体内地塞米松植入装置治疗五周后,出现了弥漫性单侧巨细胞病毒性视网膜炎。左眼检查显示弥漫性视网膜出血、视网膜血管变细和迂曲,以及视网膜上方变白。患者通过玻璃体内膦甲酸系列注射和口服缬更昔洛韦成功治疗,在就诊后12周观察到病情好转。在9个月的随访中,患者的视力和检查结果保持稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95a3/11182273/0e7ee4c0198f/fopht-04-1354104-g001.jpg

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