别构调节激酶活性。
Allosteric regulation of kinase activity.
机构信息
eLife Sciences Publications, Cambridge, United Kingdom.
出版信息
Elife. 2024 Jul 10;13:e97084. doi: 10.7554/eLife.97084.
Abstract
The articles in this special issue highlight how modern cellular, biochemical, biophysical and computational techniques are allowing deeper and more detailed studies of allosteric kinase regulation.
摘要
本期特刊中的文章重点介绍了现代细胞、生化、生物物理和计算技术如何能够实现对别构激酶调节的更深入和更详细的研究。
相似文献
1
Allosteric regulation of kinase activity.别构调节激酶活性。
Elife. 2024 Jul 10;13:e97084. doi: 10.7554/eLife.97084.
2
Pseudokinases-remnants of evolution or key allosteric regulators?假激酶——进化的残余还是关键的变构调节剂？
Curr Opin Struct Biol. 2010 Dec;20(6):772-81. doi: 10.1016/j.sbi.2010.10.001. Epub 2010 Nov 10.
3
Allosteric protein kinase regulation by pseudokinases: insights from STRAD.别构蛋白激酶的调节：来自 STRAD 的见解。
Sci Signal. 2010 Mar 2;3(111):pe8. doi: 10.1126/scisignal.3111pe8.
4
Allosteric regulation of kinase activity in living cells.变构调节活细胞中的激酶活性。
Elife. 2023 Nov 9;12:RP90574. doi: 10.7554/eLife.90574.
5
Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.靶向激酶的新方法：变构抑制、变构激活和假激酶。
Future Med Chem. 2014 Apr;6(5):541-61. doi: 10.4155/fmc.13.216.
6
Engineered allosteric activation of kinases in living cells.在活细胞中工程化变构激活激酶。
Nat Biotechnol. 2010 Jul;28(7):743-7. doi: 10.1038/nbt.1639. Epub 2010 Jun 27.
7
Evolutionary variation and adaptation in a conserved protein kinase allosteric network: implications for inhibitor design.保守蛋白激酶变构网络中的进化变异与适应性：对抑制剂设计的启示
Biochim Biophys Acta. 2013 Jul;1834(7):1322-9. doi: 10.1016/j.bbapap.2013.02.040. Epub 2013 Mar 14.
8
The secret life of kinases: insights into non-catalytic signalling functions from pseudokinases.激酶的隐秘生活：来自假激酶的非催化信号功能洞察
Biochem Soc Trans. 2017 Jun 15;45(3):665-681. doi: 10.1042/BST20160331.
9
Structure- and Similarity-Based Survey of Allosteric Kinase Inhibitors, Activators, and Closely Related Compounds.基于结构和相似性的变构激酶抑制剂、激动剂和密切相关化合物的调查。
J Med Chem. 2022 Jan 27;65(2):922-934. doi: 10.1021/acs.jmedchem.0c02076. Epub 2021 Jan 21.
10
The energy landscape analysis of cancer mutations in protein kinases.肿瘤蛋白激酶中癌症突变的能量景观分析。
PLoS One. 2011;6(10):e26071. doi: 10.1371/journal.pone.0026071. Epub 2011 Oct 6.
本文引用的文献
1
Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock.磷酸化、无序和相分离控制真菌生物钟中频率的行为。
Elife. 2024 Mar 25;12:RP90259. doi: 10.7554/eLife.90259.
2
Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens.嘌呤核苷替代 cAMP 在粘体动物病原体蛋白激酶 A 的变构调节中。
Elife. 2024 Mar 22;12:RP91040. doi: 10.7554/eLife.91040.
3
Location, location, location: Protein kinase nanoclustering for optimised signalling output.位置、位置、位置：优化信号输出的蛋白激酶纳米簇集。
Elife. 2024 Jan 11;13:e93902. doi: 10.7554/eLife.93902.
4
Probing ligand selectivity in pathogens.探测病原体中的配体选择性。
Elife. 2023 Dec 21;12:e94720. doi: 10.7554/eLife.94720.
5
Ulk4 promotes Shh signaling by regulating Stk36 ciliary localization and Gli2 phosphorylation.Ulk4 通过调控 Stk36 的纤毛定位和 Gli2 的磷酸化促进 Shh 信号通路。
Elife. 2023 Dec 14;12:RP88637. doi: 10.7554/eLife.88637.
6
Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases.深入了解 DCLK 家族激酶中同工型特异性“超激发”的机制和进化观点。
Elife. 2023 Oct 26;12:RP87958. doi: 10.7554/eLife.87958.
7
CaMKII autophosphorylation can occur between holoenzymes without subunit exchange.CaMKII 自动磷酸化可以在全酶之间发生，而无需亚基交换。
Elife. 2023 Aug 11;12:e86090. doi: 10.7554/eLife.86090.
8
A back-door insight into the modulation of Src kinase activity by the polyamine spermidine.通过多胺亚精胺对Src 激酶活性的调节获得后门式见解。
Elife. 2023 Jun 30;12:e85872. doi: 10.7554/eLife.85872.
9
Application of a Theory of Enzyme Specificity to Protein Synthesis.酶特异性理论在蛋白质合成中的应用。
Proc Natl Acad Sci U S A. 1958 Feb;44(2):98-104. doi: 10.1073/pnas.44.2.98.
10
Conversion of phosphorylase b to phosphorylase a in muscle extracts.肌肉提取物中磷酸化酶b向磷酸化酶a的转化。
J Biol Chem. 1955 Sep;216(1):121-32.
Zotero 插件