Department of Medicine, Johns Hopkins University, Baltimore, MD.
The Aurum Institute, Johannesburg, South Africa.
J Acquir Immune Defic Syndr. 2024 Aug 15;96(5):465-471. doi: 10.1097/QAI.0000000000003456.
People in correctional settings are a key population for HIV epidemic control. We sought to demonstrate scale-up of universal test and treat in correctional facilities in South Africa and Zambia through a virtual cross-sectional analysis.
We used routine data on 2 dates: At the start of universal test and treat implementation (time 1, T1) and 1 year later (time 2, T2). We obtained correctional facility census lists for the selected dates and matched HIV testing and treatment data to generate virtual cross-sections of HIV care continuum indicators.
In the South African site, there were 4193 and 3868 people in the facility at times T1 and T2; 43% and 36% were matched with HIV testing or treatment data, respectively. At T1 and T2, respectively, 1803 (43%) and 1386 (36%) had known HIV status, 804 (19%) and 845 (21%) were known to be living with HIV, and 60% and 56% of those with known HIV were receiving antiretroviral therapy (ART). In the Zambian site, there were 1467 and 1366 people in the facility at times T1 and T2; 58% and 92% were matched with HIV testing or treatment data, respectively. At T1 and T2, respectively, 857 (59%) and 1263 (92%) had known HIV status, 277 (19%) and 647 (47%) were known to be living with HIV, and 68% and 68% of those with known HIV were receiving ART.
This virtual cross-sectional analysis identified gaps in HIV testing coverage, and ART initiation that was not clearly demonstrated by prior cohort-based studies.
在押人员是艾滋病毒疫情控制的重点人群。我们试图通过虚拟的横断面分析,展示南非和赞比亚惩教设施中普遍检测和治疗的扩大规模。
我们使用了两个日期的常规数据:在普遍检测和治疗实施开始时(时间 1,T1)和一年后(时间 2,T2)。我们获得了选定日期的惩教设施普查名单,并将 HIV 检测和治疗数据与之匹配,以生成 HIV 护理连续体指标的虚拟横断面。
在南非现场,T1 和 T2 时设施中分别有 4193 人和 3868 人;分别有 43%和 36%的人匹配了 HIV 检测或治疗数据。T1 和 T2 时,分别有 1803 人(43%)和 1386 人(36%)已知 HIV 状况,804 人(19%)和 845 人(21%)已知患有 HIV,60%和 56%的已知 HIV 患者正在接受抗逆转录病毒治疗(ART)。在赞比亚现场,T1 和 T2 时设施中分别有 1467 人和 1366 人;分别有 58%和 92%的人匹配了 HIV 检测或治疗数据。T1 和 T2 时,分别有 857 人(59%)和 1263 人(92%)已知 HIV 状况,277 人(19%)和 647 人(47%)已知患有 HIV,68%和 68%的已知 HIV 患者正在接受 ART。
这种虚拟的横断面分析发现了 HIV 检测覆盖范围和 ART 起始方面的差距,这在之前基于队列的研究中没有明确显示。