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施蒂里亚州碘化物的尿排泄与甲状腺肿发病率——强制推行碘化盐预防措施20年后的研究

[Urinary excretion of iodide and incidence of goiter in Styria--studies 20 years after the introduction of compulsory iodinated salt prophylaxis].

作者信息

Lind P, Klima G, Wakonig P, Wawschinek O, Eber O

出版信息

Acta Med Austriaca. 1985;12(2):45-50.

PMID:3898698
Abstract

20 years after introduction of iodized salt prophylaxis by law in Austria the iodine supply of 6 to 19 year-old school children in Styria was examined. In this study we compared the goitre incidence and urine iodine excretion in children from regions with low iodine intake (locations Graz and Oberwölz) with those of an area where iodine supply was augmented by drinking local iodine containing mineral water (area of Sicheldorf). A modified ceric ion arsenate method was applied for determining urinary iodine excretion. Both in the city of Graz and the rural locality of Oberwölz there still exists an iodine deficiency, grade I (Urine iodine excretion of 50 and 65 micrograms I/g Cr respectively). The goitre incidence in 6 to 10 year olds in Graz amounted to only 4%, while Oberwölz records 8%. This figure in juveniles was relatively high already with 12% in Graz and 15% in Oberwölz. The age group of 15 to 19 years at the Graz secondary school showed a goitre incidence of 12%. The results of the 6 to 10 year olds in the Sicheldorf area recorded a goitre incidence of 4%. Urinary iodine excretion in Sicheldorf: 132,64 micrograms J/g Kre.

摘要

在奥地利依法推行碘盐预防措施20年后,对施蒂利亚州6至19岁学童的碘供应情况进行了检查。在本研究中,我们比较了碘摄入量低的地区(格拉茨和奥伯沃尔茨)儿童的甲状腺肿发病率和尿碘排泄情况,与通过饮用当地含碘矿泉水增加碘供应的地区(锡赫尔多夫地区)的儿童进行了比较。采用改良的砷酸铈法测定尿碘排泄量。在格拉茨市和奥伯沃尔茨农村地区,碘缺乏情况仍然存在,为I级(尿碘排泄量分别为50和65微克碘/克肌酐)。格拉茨6至10岁儿童的甲状腺肿发病率仅为4%,而奥伯沃尔茨为8%。青少年中的这一数字相对较高,格拉茨为12%,奥伯沃尔茨为15%。格拉茨中学15至19岁年龄组的甲状腺肿发病率为12%。锡赫尔多夫地区6至10岁儿童的甲状腺肿发病率为4%。锡赫尔多夫的尿碘排泄量:132.64微克碘/克肌酐。

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