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多病共存患者的社会参与与抑郁症状之间的关系:认知功能和日常生活活动的连锁中介作用。

Relationship between social participation and depressive symptoms in patients with multimorbidity: the chained mediating role of cognitive function and activities of daily living.

机构信息

School of Public Health, Shandong Second Medical University, Weifang, Shandong, China.

Shandong Cancer Research Institute (Shandong Tumor Hospital), Jinan, Shandong, China.

出版信息

BMC Public Health. 2024 Jul 10;24(1):1844. doi: 10.1186/s12889-024-19157-7.

Abstract

OBJECTIVE

The potential mechanisms linking social participation and depressive symptoms in Chinese individuals with multimorbidity are not yet fully understood. This study aims to explore how cognitive function and activities of daily living (ADLs) mediate the relationship between social participation and depressive symptoms in individuals with multimorbidity.

METHODS

We selected 3782 participants with multimorbidity from the 2018 China Health and Retirement Longitudinal Study. Data related to social participation, cognitive function, ADLs, and depressive symptoms were extracted. Regression and Bootstrap analyses were used to explore the sequential mediating effects of social participation, cognitive function, ADLs, and depressive symptoms.

RESULTS

(1) There was a significant correlation between social participation, cognitive function, activities of daily living, and depressive symptoms (p < 0.01). (2) Social participation directly affected depressive symptoms (β = -0.205, p < 0.05). (3) Cognitive function (β = -0.070, p < 0.01) and activities of daily living (β = -0.058, p < 0.01) played separate mediating roles in the effect of social participation on depressive symptoms. (4) Cognitive function and activities of daily living had a chain-mediated role in the relationship between social participation and depressive symptoms in patients with multimorbidity (β = -0.020, p < 0.01).

CONCLUSION

A chained mediating effect was found between cognitive function, ADLs, social participation, and depressive symptoms in patients with multimorbidity. Social participation was found to improve the cognitive function of patients with multimorbidity, which in turn enhanced their daily life activities and ultimately alleviated their depressive symptoms.

摘要

目的

在中国患有多种疾病的人群中,社会参与与抑郁症状之间的潜在机制尚不完全清楚。本研究旨在探讨认知功能和日常生活活动(ADL)如何在患有多种疾病的个体中中介社会参与与抑郁症状之间的关系。

方法

我们从 2018 年中国健康与退休纵向研究中选择了 3782 名患有多种疾病的参与者。提取了与社会参与、认知功能、ADL 和抑郁症状相关的数据。回归和 Bootstrap 分析用于探索社会参与、认知功能、ADL 和抑郁症状之间的顺序中介效应。

结果

(1)社会参与、认知功能、日常生活活动和抑郁症状之间存在显著相关性(p<0.01)。(2)社会参与直接影响抑郁症状(β=-0.205,p<0.05)。(3)认知功能(β=-0.070,p<0.01)和日常生活活动(β=-0.058,p<0.01)在社会参与对抑郁症状的影响中发挥了单独的中介作用。(4)认知功能和日常生活活动在患有多种疾病的个体的社会参与与抑郁症状之间具有链式中介作用(β=-0.020,p<0.01)。

结论

在患有多种疾病的患者中,发现认知功能、ADL、社会参与和抑郁症状之间存在链式中介效应。社会参与被发现可以改善患有多种疾病的患者的认知功能,进而增强他们的日常生活活动,最终缓解他们的抑郁症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9873/11234698/5acab94834d1/12889_2024_19157_Fig1_HTML.jpg

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