Engle J C, Lifland P W, Schleupner C J
Antimicrob Agents Chemother. 1985 Jul;28(1):146-8. doi: 10.1128/AAC.28.1.146.
Ceftazidime and cefamandole were compared in the treatment of pneumonia. The median MIC of ceftazidime for all Streptococcus pneumoniae (n = 17) and Haemophilus influenzae (n = 10) isolates was 0.125 microgram/ml. All other isolates were inhibited by less than 0.5 microgram of ceftazidime per ml, with the exception of a group B streptococcus (MIC = 4 micrograms/ml). Satisfactory clinical responses were observed in 91% (20 of 22) of cefamandole-treated patients and 85% (17 of 20) of ceftazidime-treated patients.
对头孢他啶和头孢孟多治疗肺炎的效果进行了比较。头孢他啶对所有肺炎链球菌(n = 17)和流感嗜血杆菌(n = 10)分离株的MIC中位数为0.125微克/毫升。除1株B组链球菌(MIC = 4微克/毫升)外,所有其他分离株均被每毫升低于0.5微克的头孢他啶所抑制。头孢孟多治疗的患者中有91%(22例中的20例)观察到满意的临床反应,头孢他啶治疗的患者中有85%(20例中的17例)观察到满意的临床反应。