Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Beijing Office for Cancer Prevention and Control, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Vaccine. 2020 Apr 29;38(20):3665-3670. doi: 10.1016/j.vaccine.2020.03.032. Epub 2020 Mar 31.
Middle school students are recommended as the primary target population for human papillomavirus (HPV) vaccination. This study aimed to assess HPV and HPV vaccine knowledge, and to evaluate the effect of a school-based educational intervention, immediately and one year later, on HPV knowledge and vaccine acceptability among adolescents in mainland China.
A school-based interventional follow-up study was conducted in seven representative cities in mainland China from May 2015 to May 2017. "Train-the-trainer" strategy was employed to educate school teachers in this study. Students aged 13 to 14 years old were assigned to intervention classes and control classes. All students were required to complete the baseline questionnaire. Students in the intervention classes were given a 45-minute lecture regarding HPV and HPV vaccine knowledge and were then asked to complete a post-education questionnaire. One year later, all students were asked to complete the post-education questionnaire again.
Baseline HPV knowledge was low among Chinese adolescents, with only 12.6% and 15.7% of students having heard of HPV and HPV vaccines, respectively. After the intervention, the level of HPV-related knowledge increased immediately, and students with higher knowledge levels of HPV and HPV vaccines were more willing to get vaccinated. One year after the intervention, the knowledge of HPV and HPV vaccines was dramatically diminished. However, knowledge was significantly higher in intervention classes compared to control classes.
Knowledge and awareness of HPV and vaccination are generally deficient among Chinese adolescents. School-based health education was very effective in improving awareness and positive attitudes about HPV and HPV vaccines within a short time. Integrating health education on HPV into the existing school-based sexual health curriculum could be an effective way to increase HPV vaccination coverage and help to eliminate preventable HPV-associated cancers in China.
中学生被推荐为 HPV 疫苗接种的主要目标人群。本研究旨在评估 HPV 和 HPV 疫苗知识，并评估基于学校的教育干预措施对中国青少年 HPV 知识和疫苗可接受性的即时和一年后的效果。
本研究于 2015 年 5 月至 2017 年 5 月在中国大陆七个有代表性的城市进行了基于学校的干预性随访研究。本研究采用“培训师培训”策略对学校教师进行教育。将 13 至 14 岁的学生分配到干预班和对照组。所有学生都需要完成基线问卷。干预班的学生接受了 45 分钟的 HPV 和 HPV 疫苗知识讲座，然后被要求完成一份教育后问卷。一年后，所有学生被要求再次完成教育后问卷。
中国青少年 HPV 知识基础薄弱，仅有 12.6%和 15.7%的学生听说过 HPV 和 HPV 疫苗。干预后，HPV 相关知识水平立即提高，对 HPV 和 HPV 疫苗知识水平较高的学生更愿意接种疫苗。一年后，HPV 和 HPV 疫苗的知识明显减少。然而，干预组的知识水平明显高于对照组。
中国青少年对 HPV 和疫苗接种的知识和认识普遍不足。基于学校的健康教育在短时间内非常有效地提高了对 HPV 和 HPV 疫苗的认识和积极态度。将 HPV 健康教育纳入现有的学校性健康课程中，可能是提高 HPV 疫苗接种率、帮助消除中国可预防 HPV 相关癌症的有效途径。
