Universidade Federal do Ceará FortalezaCE Brazil Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Rev Bras Ginecol Obstet. 2024 Jun 27;46. doi: 10.61622/rbgo/2024rbgo42. eCollection 2024.
To evaluate the effects of surgical treatment of deep endometriosis on the metabolic profile, quality of life and psychological aspects.
Prospective observational study, carried out with women of reproductive age diagnosed with deep endometriosis, treated in a specialized outpatient clinic, from October/2020 to September/2022, at a University Hospital in Fortaleza - Brazil. Standardized questionnaires were applied to collect data on quality of life and mental health, in addition to laboratory tests to evaluate dyslipidemia and dysglycemia, at two moments, preoperatively and six months after surgery. The results were presented using tables, averages and percentages.
Thirty women with an average age of 38.5 years were evaluated. Seven quality of life domains showed improved scores: pain, control and impotence, well-being, social support, self-image, work life and sexual relations after surgery (ES ≥ 0.80). There was an improvement in mental health status with a significant reduction in anxiety and depression postoperatively. With the metabolic profile, all average levels were lower after surgery: total cholesterol 8.2% lower, LDL 12.8% lower, triglycerides 10.9% lower, and fasting blood glucose 7.3% lower (p < 0.001).
Surgical treatment of deep endometriosis improved the quality of life and psychological aspects of patients. The lipid profile of patients after laparoscopy was favorable when compared to the preoperative lipid profile.
评估深部子宫内膜异位症手术治疗对代谢特征、生活质量和心理方面的影响。
前瞻性观察研究，纳入 2020 年 10 月至 2022 年 9 月在巴西福塔雷萨一家大学医院的专门门诊就诊、被诊断为深部子宫内膜异位症的育龄期妇女。应用标准化问卷收集生活质量和心理健康数据，此外，还进行了实验室检查以评估血脂异常和糖代谢异常，分别在术前和术后 6 个月进行。结果以表格、平均值和百分比呈现。
共评估了 30 名平均年龄为 38.5 岁的女性。7 个生活质量领域的评分有所改善：手术后疼痛、控制和勃起功能障碍、幸福感、社会支持、自我形象、工作生活和性关系（ES≥0.80）。心理健康状况有所改善，术后焦虑和抑郁显著减轻。代谢特征方面，所有平均水平在手术后均降低：总胆固醇降低 8.2%，LDL 降低 12.8%，甘油三酯降低 10.9%，空腹血糖降低 7.3%（p<0.001）。
深部子宫内膜异位症的手术治疗改善了患者的生活质量和心理状况。与术前的血脂特征相比，腹腔镜手术后患者的血脂谱更有利。
