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探讨健康成年人中地中海饮食依从性与动脉僵硬之间的关联:EvasCu 研究的结果。

Exploring the Association between Mediterranean Diet Adherence and Arterial Stiffness in Healthy Adults: Findings from the EvasCu Study.

机构信息

CarVasCare Research Group (2023-GRIN-34459), Facultad de Enfermería de Cuenca, Universidad de Castilla-La Mancha, 16002 Cuenca, Spain.

Instituto Superior de Educación Física, Universidad de la República, Rivera 40000, Uruguay.

出版信息

Nutrients. 2024 Jul 6;16(13):2158. doi: 10.3390/nu16132158.

Abstract

(1) Background: Previous evidence has indicated a connection between a Mediterranean diet and cardiovascular disease. However, evidence for subclinical markers of cardiovascular disease, such as arterial stiffness, is limited. Therefore, the aim of this study was to assess the associations between adherence to the Mediterranean diet (MD), as assessed by the MEDAS-14 questionnaire, and arterial stiffness, as assessed by aortic pulse wave velocity, in healthy adults and according to sex. (2) A cross-sectional study including 386 healthy participants was performed in the EVasCu study. Adjusted and unadjusted differences in adherence to the MD and arterial stiffness were determined using Student's test and ANCOVA for the total sample and according to sex. (3) Results: Our results showed that individuals with a high adherence to the MD had a greater arterial stiffness, both in the total sample and in females, although this difference was not significant after adjusting for possible confounding variables, such as age. (4) Conclusions: Our findings indicated that, in the unadjusted analyses, healthy subjects with a high adherence to the MD showed a greater arterial stiffness. When these analyses were adjusted, no significant differences were shown in a-PWv according to the categories of MD adherence.

摘要

(1) 背景:先前的证据表明,地中海饮食与心血管疾病之间存在关联。然而,关于心血管疾病亚临床标志物(如动脉僵硬度)的证据有限。因此,本研究旨在评估 MEDAS-14 问卷评估的地中海饮食(MD)依从性与健康成年人动脉僵硬度(通过主动脉脉搏波速度评估)之间的关系,并按性别进行分析。(2) 在 EVasCu 研究中进行了一项横断面研究,共纳入 386 名健康参与者。使用 Student's t 检验和总样本及按性别进行的协方差分析(ANCOVA)确定 MD 依从性和动脉僵硬度的调整和未调整差异。(3) 结果:我们的结果表明,在总样本和女性中,MD 依从性高的个体动脉僵硬度更高,尽管在调整了可能的混杂变量(如年龄)后,这种差异并不显著。(4) 结论:我们的研究结果表明,在未调整的分析中,MD 依从性高的健康受试者动脉僵硬度更大。当对这些分析进行调整时,根据 MD 依从性的类别,a-PWv 并未显示出显著差异。

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