高强度间歇运动对心血管疾病高危个体动脉僵硬度的影响：一项荟萃分析。

Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis.

作者信息

Luo Ping, Wu Ruoshan, Gao Weifeng, Yan Weiyi, Wang Ruixue, Ye Yufang

机构信息

School of Physical Education, Wuhan Sport University, Wuhan, China.

School of Physical Education, Hunan University of Science and Technology, Xiangtan, China.

出版信息

Front Cardiovasc Med. 2024 Apr 17;11:1376861. doi: 10.3389/fcvm.2024.1376861. eCollection 2024.

DOI:10.3389/fcvm.2024.1376861

PMID:38694567

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11061535/

Abstract

OBJECTIVE

The purpose of this meta-analysis was to investigate the effect of high-intensity interval training (HIIT) on arterial stiffness (AS) and vascular function in persons at high risk of cardiovascular disease (CVD).

METHODS

We conducted a comprehensive search of randomized controlled trials (RCTs) published in electronic databases (PubMed, Web of Science, Cochrane, Embase, and Ebsco) since their inception through October 2023 to evaluate the effect of HIIT on AS and vascular function in persons at high risk for CVD. The weighted mean difference (WMD) and 95% confidence intervals (95% CI) were calculated, and heterogeneity was assessed using the test.

RESULTS

This study included 661 participants from 16 studies. HIIT significantly reduced pulse wave velocity (PWV) in persons at high risk for CVD [weighted mean difference (WMD), -0.62; 95% CI, -0.86--0.38; < 0.00001]. Subgroup analysis showed that the PWV improvement effect was better when the HIIT program was performed 2-3 times per week and the duration was controlled within 40 min [2-3 times, -0.67; 95% CI, -0.93--0.41; < 0.00001; time of duration, ≤40 min, -0.66; 95% CI, -0.91--0.41; < 0.00001]. HIIT significantly reduced systolic blood pressure (SBP, -5.43; 95% CI, -8.82--2.04; = 0.002), diastolic blood pressure (DPB, -2.96; 95% CI, -4.88--1.04; = 0.002), and resting heart rate (RHR, -4.35; 95% CI, -7.04--1.66; = 0.002), but had no significant effect on augmentation index (AIX, -2.14; 95% CI, -6.77-2.50; = 0.37).

CONCLUSION

HIIT can improve PWV in high-risk individuals with CVD and reduce SBP, DBP, and RHR, but has no significant effect on AIX. HIIT can effectively improve AS and vascular function and can be recommended as an effective method to improve AS in high-risk persons with CVD.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42023471593.

摘要

目的

本荟萃分析旨在研究高强度间歇训练（HIIT）对心血管疾病（CVD）高危人群动脉僵硬度（AS）和血管功能的影响。

方法

我们全面检索了电子数据库（PubMed、Web of Science、Cochrane、Embase和Ebsco）自创建至2023年10月发表的随机对照试验（RCT），以评估HIIT对CVD高危人群AS和血管功能的影响。计算加权平均差（WMD）和95%置信区间（95%CI），并使用检验评估异质性。

结果

本研究纳入了来自16项研究的661名参与者。HIIT显著降低了CVD高危人群的脉搏波速度（PWV）[加权平均差（WMD），-0.62；95%CI，-0.86--0.38； < 0.00001]。亚组分析表明，当HIIT计划每周进行2-3次且持续时间控制在40分钟以内时，PWV改善效果更好[2-3次，-0.67；95%CI，-0.93--0.41； < 0.00001；持续时间，≤40分钟，-0.66；95%CI，-0.91--0.41； < 0.00001]。HIIT显著降低了收缩压（SBP，-5.43；95%CI，-8.82--2.04； = 0.002）、舒张压（DBP，-2.96；95%CI，-4.88--1.04； = 0.002）和静息心率（RHR，-4.35；95%CI，-7.04--1.66； = 0.002），但对增强指数（AIX，-2.14；95%CI，-6.77-2.50； = 0.37）无显著影响。