间质干细胞及其衍生产品在衰老和疾病中的作用。
Mesenchymal Stem Cells and Their Derived Products in Ageing and Diseases.
机构信息
Research Unit, Fundación Hospital de Jove, Avda. Eduardo Castro, 161, 33920 Gijón, Spain.
出版信息
Int J Mol Sci. 2024 Jun 26;25(13):6979. doi: 10.3390/ijms25136979.
Abstract
Despite the enormous efforts of the pharmaceutical industry in the generation of new drugs (55 new ones last year) [...].
摘要
尽管制药行业在研发新药方面付出了巨大努力（去年有 55 种新药）[... ]。
相似文献
1
Mesenchymal Stem Cells and Their Derived Products in Ageing and Diseases.间质干细胞及其衍生产品在衰老和疾病中的作用。
Int J Mol Sci. 2024 Jun 26;25(13):6979. doi: 10.3390/ijms25136979.
2
Potential of Mesenchymal Stem Cells in the Rejuvenation of the Aging Immune System.间充质干细胞在衰老免疫系统复壮中的潜力。
Int J Mol Sci. 2021 May 27;22(11):5749. doi: 10.3390/ijms22115749.
3
Adipose mesenchymal stem cells. Their characteristics and potential application in tissue repair.脂肪间充质干细胞。其特征及在组织修复中的潜在应用。
Pol Orthop Traumatol. 2012 Dec 15;77:97-9.
4
Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging.用于皮肤病学适应症和皮肤衰老临床应用的脂肪组织间充质干细胞
Int J Mol Sci. 2017 Jan 20;18(1):208. doi: 10.3390/ijms18010208.
5
"Next-generation" mesenchymal stem or stromal cells for the in vivo delivery of bioactive factors: progressing toward the clinic.用于生物活性因子体内递送的“下一代”间充质干细胞或基质细胞：向临床迈进
Transfusion. 2016 Apr;56(4):15S-7S. doi: 10.1111/trf.13564.
6
Adipose derived mesenchymal stem cells along with Alpinia oxyphylla extract alleviate mitochondria-mediated cardiac apoptosis in aging models and cardiac function in aging rats.脂肪间充质干细胞联合益智仁提取物减轻衰老模型中线粒体介导的心脏细胞凋亡及改善衰老大鼠心功能。
J Ethnopharmacol. 2021 Jan 10;264:113297. doi: 10.1016/j.jep.2020.113297. Epub 2020 Aug 22.
7
Mesenchymal Stem/Progenitor Cells and Their Derivates in Tissue Regeneration-Part II.间质干细胞/祖细胞及其在组织再生中的衍生物-第二部分。
Int J Mol Sci. 2024 Apr 30;25(9):4937. doi: 10.3390/ijms25094937.
8
Heterogeneity of cell therapy products.细胞治疗产品的异质性。
S Afr Med J. 2019 Sep 10;109(8b):24-28. doi: 10.7196/SAMJ.2019.v109i8b.13822.
9
Increased migratory and homing abilities of neural and mesenchymal stem cell populations by transient cell modifications: Preclinical progress and clinical relevance.通过瞬时细胞修饰增强神经和间充质干细胞群体的迁移和归巢能力：临床前进展及临床相关性
EBioMedicine. 2020 Oct;60:103022. doi: 10.1016/j.ebiom.2020.103022. Epub 2020 Sep 24.
10
Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options.基于间充质基质细胞的产品：挑战和临床治疗选择。
Int J Mol Sci. 2024 May 31;25(11):6063. doi: 10.3390/ijms25116063.
引用本文的文献
1
Progress in the application of mesenchymal stem cells to attenuate apoptosis in diabetic kidney disease.间充质干细胞在减轻糖尿病肾病细胞凋亡方面的应用进展
World J Diabetes. 2025 Jun 15;16(6):105711. doi: 10.4239/wjd.v16.i6.105711.
2
The mechanism of telomerase Cajal body protein 1 regulating senescence of mouse bone marrow mesenchymal stem cells.端粒酶卡哈尔体蛋白1调控小鼠骨髓间充质干细胞衰老的机制。
Stem Cell Res Ther. 2025 May 30;16(1):267. doi: 10.1186/s13287-025-04406-2.
3
Exploring the dermatological applications of human mesenchymal stem cell secretome: a comprehensive review.探索人间充质干细胞分泌组的皮肤病学应用：一项综述
Stem Cell Res Ther. 2025 Apr 12;16(1):177. doi: 10.1186/s13287-025-04311-8.
本文引用的文献
1
Bibliometric and visualized analysis of the applications of exosomes based drug delivery.基于外泌体的药物传递应用的文献计量和可视化分析。
Biomed Pharmacother. 2024 Jul;176:116803. doi: 10.1016/j.biopha.2024.116803. Epub 2024 May 23.
2
Intranasal Administration of Mesenchymal Stem Cell-Derived Exosome Alleviates Hypoxic-Ischemic Brain Injury.间充质干细胞衍生外泌体的鼻内给药减轻缺氧缺血性脑损伤。
Pharmaceutics. 2024 Mar 23;16(4):446. doi: 10.3390/pharmaceutics16040446.
3
Synergistic effect of human uterine cervical mesenchymal stem cell secretome and paclitaxel on triple negative breast cancer.人子宫颈间质干细胞分泌组与紫杉醇对三阴性乳腺癌的协同作用。
Stem Cell Res Ther. 2024 Apr 25;15(1):121. doi: 10.1186/s13287-024-03717-0.
4
Mesenchymal stem cell-derived exosomes as a new drug carrier for the treatment of spinal cord injury: A review.间充质干细胞衍生的外泌体作为治疗脊髓损伤的新型药物载体：综述。
Chin J Traumatol. 2024 May;27(3):134-146. doi: 10.1016/j.cjtee.2024.03.009. Epub 2024 Mar 26.
5
The Pharmaceutical Industry in 2023: An Analysis of FDA Drug Approvals from the Perspective of Molecules.2023 年的制药行业：从分子角度分析 FDA 药物批准。
Molecules. 2024 Jan 25;29(3):585. doi: 10.3390/molecules29030585.
6
Stem Cell-Based Therapy and Cell-Free Therapy as an Alternative Approach for Cardiac Regeneration.基于干细胞的疗法和无细胞疗法作为心脏再生的替代方法。
Stem Cells Int. 2023 Nov 2;2023:2729377. doi: 10.1155/2023/2729377. eCollection 2023.
7
Perspectives on Aging and Quality of Life.衰老与生活质量的观点
Healthcare (Basel). 2023 Jul 26;11(15):2131. doi: 10.3390/healthcare11152131.
8
Applications of multi-omics analysis in human diseases.多组学分析在人类疾病中的应用。
MedComm (2020). 2023 Jul 31;4(4):e315. doi: 10.1002/mco2.315. eCollection 2023 Aug.
9
Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives.作为基于天然纳米载体的药物递送系统的外泌体：最新见解与未来展望
3 Biotech. 2023 Mar;13(3):101. doi: 10.1007/s13205-023-03521-2. Epub 2023 Feb 27.
10
Mesenchymal Stem Cell-Derived Secretome: A Potential Therapeutic Option for Autoimmune and Immune-Mediated Inflammatory Diseases.间质干细胞衍生的分泌组：一种用于自身免疫和免疫介导的炎症性疾病的潜在治疗选择。
Cells. 2022 Jul 26;11(15):2300. doi: 10.3390/cells11152300.
Zotero 插件