State Key Laboratory of Animal Biotech Breeding and Frontier Science Center for Molecular Design Breeding, National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affairs, Department of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Int J Mol Sci. 2024 Jun 28;25(13):7154. doi: 10.3390/ijms25137154.
Currently, there is a dearth of in-depth analysis and research on the impact of canthaxanthin on the production performance, egg quality, physical characteristics, and offspring health of laying hens. Furthermore, the metabolic mechanism of cantharidin in the body remains unclear. Therefore, to solve the above issues in detail, our study was conducted with a control group (C group), a low-dose canthaxanthin group (L group), and a high-dose canthaxanthin group (H group), each fed for a period of 40 days. Production performance was monitored during the experiment, in which L and H groups showed a significant increase in ADFI. Eggs were collected for quality analysis, revealing no significant differences in qualities except for yolk color (YC). The YC of the C group almost did not change, ranging from 6.08 to 6.20; however, the trend in YC change in other groups showed an initial intense increase, followed by a decrease, and eventually reached dynamic equilibrium. By detecting the content of canthaxanthin in the yolk, the YC change trend was found to be correlated with canthaxanthin levels in the yolk. The content of unsaturated fatty acid increased slightly in L and H groups. Following the incubation period, the physical characteristics and blood biochemical indices of chicks were evaluated. It was observed that the shank color of chicks in the L and H groups was significantly higher than that in the C group at birth. However, by the 35th day, there were no significant differences in shank color among the three groups. Further investigation into the metabolic mechanism involving canthaxanthin revealed that the substance underwent incomplete metabolism upon entering the body, resulting in its accumulation as well as metabolic by-product accumulation in the yolk. In summary, this study highlighted the importance of understanding canthaxanthin's role in production performance, egg quality, and offspring health, providing valuable insights for breeders to optimize feeding strategies.
目前，对于角黄素对蛋鸡生产性能、蛋品质、体况和后代健康的影响，缺乏深入的分析和研究。此外，角黄素在体内的代谢机制尚不清楚。因此，为了详细解决上述问题，我们的研究设置了对照组（C 组）、低剂量角黄素组（L 组）和高剂量角黄素组（H 组），每组饲喂 40 天。实验过程中监测生产性能，L 组和 H 组 ADFI 显著增加。收集鸡蛋进行品质分析，除蛋黄颜色（YC）外，其他品质无显著差异。C 组的 YC 几乎不变，范围在 6.08 到 6.20；然而，其他组的 YC 变化趋势呈先急剧增加，后减少，最终达到动态平衡。通过检测蛋黄中角黄素的含量，发现 YC 变化趋势与蛋黄中角黄素水平相关。L 组和 H 组不饱和脂肪酸含量略有增加。经过孵化期后，评估小鸡的体况和血液生化指标。结果发现，L 组和 H 组小鸡的小腿颜色在出生时明显高于 C 组，但到第 35 天时，三组小鸡的小腿颜色无显著差异。进一步研究角黄素的代谢机制表明，该物质进入体内后发生不完全代谢，导致其在体内积累以及代谢产物在蛋黄中积累。综上所述，本研究强调了了解角黄素在生产性能、蛋品质和后代健康中的作用的重要性，为饲养者优化饲养策略提供了有价值的见解。
