Nie Fang, Ji Yu, Sun Hao, Lee Zeqian, Zhang Yan, Han Wei, Ding YuChuan
Central Laboratory, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Department of General Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Lasers Med Sci. 2024 Jul 13;39(1):180. doi: 10.1007/s10103-024-04121-z.
This study investigates the impact of Photobiomodulation (PBM) at different wavelengths on non-superficial cancer cells. Utilizing three laser protocols (650 nm, 810 nm, and 915 nm), the research explores cytotoxic effects, ROS generation, and cell migration. Results reveal varied responses across cell lines, with 810 nm PBM inducing significant ROS levels and inhibiting PAN-1 cell migration. The study suggests potential therapeutic applications for PBM in non-superficial cancers, emphasizing the need for further exploration in clinical settings.
本研究调查了不同波长的光生物调节（PBM）对非浅表癌细胞的影响。利用三种激光方案（650纳米、810纳米和915纳米），该研究探索了细胞毒性作用、活性氧（ROS）生成和细胞迁移。结果显示不同细胞系有不同反应，810纳米的PBM可诱导显著的ROS水平并抑制PAN-1细胞迁移。该研究表明PBM在非浅表癌症中具有潜在的治疗应用，强调了在临床环境中进一步探索的必要性。
