一种新型温度控制软性输尿管镜系统的体内评估，用于在软性输尿管镜检查期间监测和控制肾内温度。

An In Vivo Assessment of a Novel Temperature Control Flexible Ureteroscope System for Monitoring and Controlling Intrarenal Temperature During Flexible Ureteroscopy.

机构信息

Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Provincial Clinical Research Center for Urological Diseases, Guangzhou, Guangdong, China.

出版信息

Urology. 2024 Sep;191:38-44. doi: 10.1016/j.urology.2024.07.011. Epub 2024 Jul 11.

DOI:10.1016/j.urology.2024.07.011

PMID:39002847

Abstract

OBJECTIVE

To evaluate the efficacy of a novel temperature control flexible ureteroscope system in the precise monitoring and control of intrarenal temperature (IRT) during ureteroscopy.

METHODS

We developed a novel temperature control flexible ureteroscope system (PT-Scope), including a temperature-monitoring ureteroscope and a irrigation-suction platform for temperature regulation. A porcine thermometry model was established to observe temperature changes under varying holmium laser powers (10, 20, 30 W) and irrigation rates (0, 20, 50 mL/min), utilizing percutaneous nephrostomy thermometry and PT-Scope measurements, with subsequent evaluation of temperature variations at different distances from the laser fiber tip. A porcine kidney stone model was established while porcine was randomly assigned to two groups: In the temperature control group, PT-Scope was connected to the irrigation-suction platform with temperature regulation, while in the nontemperature control group without temperature regulation. Comparative analysis was performed to evaluate differences in IRT between the two groups.

RESULTS

Across various laser powers and irrigation rates, the temperature measurement capability of the PT-Scope was precise, demonstrating consistency with percutaneous nephrostomy temperature measurements. The temperature obtained from the PT-Scope reflect the temperature approximately 0.05 cm away from the fiber tip, whereas temperatures close to fiber tip were significantly higher. The peak temperature of the temperature control group vs nontemperature control group were 31.70 ± 2.609°C and 44.37 ± 3.318 °C, respectively (P < 0.01). The mean temperature of the temperature control group vs nontemperature control group was 27.40 ± 2.107 °C vs 35.9 ± 1.921 °C (P < 0.01).

CONCLUSION

PT-Scope has demonstrated the capability to precisely monitor and control IRT within a safe threshold.

摘要

目的

评估新型温度控制软性输尿管镜系统在输尿管镜检查中精确监测和控制肾内温度（IRT）的效果。

方法

我们开发了一种新型温度控制软性输尿管镜系统（PT-Scope），包括温度监测输尿管镜和用于温度调节的冲洗-抽吸平台。建立了猪测温模型，观察不同钬激光功率（10、20、30 W）和冲洗速度（0、20、50 mL/min）下的温度变化，利用经皮肾穿刺测温法和 PT-Scope 测量法，随后评估激光纤维尖端不同距离处的温度变化。建立了猪肾结石模型，将猪随机分为两组：温度控制组，PT-Scope 通过温度调节连接到冲洗-抽吸平台；非温度控制组，无温度调节。对两组之间的 IRT 差异进行了比较分析。

结果

在各种激光功率和冲洗速度下，PT-Scope 的温度测量能力精确，与经皮肾穿刺温度测量结果一致。PT-Scope 获得的温度反映了距光纤尖端约 0.05 cm 处的温度，而接近光纤尖端的温度则明显更高。温度控制组和非温度控制组的峰值温度分别为 31.70±2.609°C 和 44.37±3.318°C（P<0.01）。温度控制组和非温度控制组的平均温度分别为 27.40±2.107°C 和 35.9±1.921°C（P<0.01）。