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植入式心脏监测器和无导线起搏器在间歇性高度房室传导阻滞引起的晕厥中的应用:一例报告。

Implantable cardiac monitor and leadless pacemaker in the management of syncope due to intermittent high-degree atrioventricular block: a case report.

机构信息

Geriatric Diseases Institute of Chengdu/Cancer Prevention and Treatment Institute of Chengdu, Department of Cardiology, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu, 611137, China.

出版信息

J Cardiothorac Surg. 2024 Jul 13;19(1):443. doi: 10.1186/s13019-024-02962-x.

DOI:10.1186/s13019-024-02962-x
PMID:39003494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11245764/
Abstract

BACKGROUND

Lead dislodgements, tricuspid valve failure, and wound infections are prominent issues addressed by leadless pacemakers (LPM). These devises have emerged as viable alternatives to conventional transvenous pacemakers. LPMs offer minimized complications and effective pacing, particularly beneficial for elderly patients with a low body mass index (BMI) who are at heightened infection of risk. The Micra AV leadless pacemaker was released in the US in 2020, featuring a VDD pacing mode akin to conventional pacemakers. It senses atrial activity to pace ventricular beats while maintaining the natural atrioventricular activation sequence. Micra AV achieves atrioventricular synchronization through mechanical sensing principles. Ongoing research aims to assess its efficacy, implantation feasibility, and clinical safety.

CASE PRESENTATION

An 83-year-old man with a history of syncope was the focus of this case study. An implantable cardiac monitor (ICM) recorded occasional high-degree atrioventricular block in the patient. Subsequently, the Micra AV was implanted via the left femoral vein, and its settings were adjusted in accordance with data obtained from the ICM. No significant issues regarding pacing threshold or impedance were found during the follow-up examinations post-surgery. Importantly, the patient experienced a noticeable reduction in symptoms compared to before the implantation.

DISCUSSION

This case underscores the significance of ICM monitoring in elucidating cardiac events leading to syncope and guiding appropriate treatment. It also highlights the successful outcomes and reliable implantation of the Micra AV for managing high-degree atrioventricular block. This study contributes to the growing body of evidence supporting the adoption of leadless pacemakers as a viable option for patients requiring cardiac pacing, particularly those vulnerable to complications associated with traditional pacemakers. It provides real-world evidence of Micra AV's efficacy and safety, further validating its role in clinical practice.

摘要

背景

无导线起搏器(LPM)主要解决了导线脱位、三尖瓣功能障碍和伤口感染等问题。这些设备已成为传统经静脉起搏器的可行替代品。LPM 可减少并发症并实现有效的起搏,特别适用于身体质量指数(BMI)较低的老年患者,这些患者感染风险较高。2020 年,美国推出了 Micra AV 无导线起搏器,采用类似于传统起搏器的 VDD 起搏模式。它通过机械感知原理感知心房活动,以起搏心室搏动,同时保持自然的房室激活顺序。Micra AV 通过机械感知原理实现房室同步。目前正在进行研究,以评估其疗效、植入可行性和临床安全性。

病例介绍

本病例研究的对象是一位 83 岁的晕厥史男性患者。植入式心脏监测器(ICM)记录到患者偶尔出现高度房室传导阻滞。随后,通过左股静脉植入 Micra AV,并根据 ICM 获得的数据调整其设置。术后随访检查未发现起搏阈值或阻抗有明显问题。重要的是,与植入前相比,患者的症状明显减轻。

讨论

本病例强调了 ICM 监测在阐明导致晕厥的心脏事件并指导适当治疗方面的重要性。它还突出了 Micra AV 成功的植入结果和可靠的性能,可用于治疗高度房室传导阻滞。该研究为越来越多的证据提供了支持,证明无导线起搏器是需要心脏起搏的患者的可行选择,特别是那些易受传统起搏器相关并发症影响的患者。它提供了 Micra AV 的疗效和安全性的真实世界证据,进一步验证了其在临床实践中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/da0c3c5ab1bf/13019_2024_2962_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/5ef6f1f4523d/13019_2024_2962_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/c9531c84038f/13019_2024_2962_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/70fd302397b6/13019_2024_2962_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/da0c3c5ab1bf/13019_2024_2962_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/5ef6f1f4523d/13019_2024_2962_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/c9531c84038f/13019_2024_2962_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/70fd302397b6/13019_2024_2962_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3bd/11245764/da0c3c5ab1bf/13019_2024_2962_Fig4_HTML.jpg

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本文引用的文献

1
Leadless or Conventional Transvenous Ventricular Permanent Pacemakers: A Nationwide Matched Control Study.无导线或传统经静脉心室永久起搏器:全国匹配对照研究。
J Am Heart Assoc. 2022 Aug 16;11(16):e025339. doi: 10.1161/JAHA.122.025339. Epub 2022 Aug 5.
2
2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.2021年欧洲心脏病学会心脏起搏与心脏再同步治疗指南。
Eur Heart J. 2021 Sep 14;42(35):3427-3520. doi: 10.1093/eurheartj/ehab364.
3
Left femoral venous access for leadless pacemaker implantation: patient characteristics and outcomes.
经左侧股静脉入路植入无导线起搏器:患者特征与结局。
Europace. 2021 Sep 8;23(9):1456-1461. doi: 10.1093/europace/euab083.
4
Atrioventricular Synchronous Pacing Using a Leadless Ventricular Pacemaker: Results From the MARVEL 2 Study.使用无导线心室起搏器实现房室同步起搏:MARVEL 2 研究结果。
JACC Clin Electrophysiol. 2020 Jan;6(1):94-106. doi: 10.1016/j.jacep.2019.10.017. Epub 2019 Nov 11.
5
Accelerometer-based atrioventricular synchronous pacing with a ventricular leadless pacemaker: Results from the Micra atrioventricular feasibility studies.基于加速度计的房室同步起搏与无导线心室起搏器:Micra 房室可行性研究结果。
Heart Rhythm. 2018 Sep;15(9):1363-1371. doi: 10.1016/j.hrthm.2018.05.004. Epub 2018 May 11.
6
2018 ESC Guidelines for the diagnosis and management of syncope.2018年欧洲心脏病学会晕厥诊断和管理指南。
Eur Heart J. 2018 Jun 1;39(21):1883-1948. doi: 10.1093/eurheartj/ehy037.