Gavidia Marino, Zhu Hongling, Montanari Arthur N, Fuentes Jesús, Cheng Cheng, Dubner Sergio, Chames Martin, Maison-Blanche Pierre, Rahman Md Moklesur, Sassi Roberto, Badilini Fabio, Jiang Yinuo, Zhang Shengjun, Zhang Hai-Tao, Du Hao, Teng Basi, Yuan Ye, Wan Guohua, Tang Zhouping, He Xin, Yang Xiaoyun, Goncalves Jorge
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367 Belvaux, Luxembourg.
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Patterns (N Y). 2024 Apr 18;5(6):100970. doi: 10.1016/j.patter.2024.100970. eCollection 2024 Jun 14.
Atrial fibrillation (AF), the most prevalent cardiac rhythm disorder, significantly increases hospitalization and health risks. Reverting from AF to sinus rhythm (SR) often requires intensive interventions. This study presents a deep-learning model capable of predicting the transition from SR to AF on average 30.8 min before the onset appears, with an accuracy of 83% and an F1 score of 85% on the test data. This performance was obtained from R-to-R interval signals, which can be accessible from wearable technology. Our model, entitled Warning of Atrial Fibrillation (WARN), consists of a deep convolutional neural network trained and validated on 24-h Holter electrocardiogram data from 280 patients, with 70 additional patients used for testing and further evaluation on 33 patients from two external centers. The low computational cost of WARN makes it ideal for integration into wearable technology, allowing for continuous heart monitoring and early AF detection, which can potentially reduce emergency interventions and improve patient outcomes.
心房颤动(AF)是最常见的心律失常,会显著增加住院率和健康风险。从房颤恢复到窦性心律(SR)通常需要强化干预。本研究提出了一种深度学习模型,该模型能够在房颤发作前平均30.8分钟预测从SR到AF的转变,在测试数据上的准确率为83%,F1分数为85%。这一性能是从R-R间期信号中获得的,而这些信号可通过可穿戴技术获取。我们的模型名为心房颤动预警(WARN),由一个深度卷积神经网络组成,该网络在280名患者的24小时动态心电图数据上进行训练和验证,另有70名患者用于测试,并对来自两个外部中心的33名患者进行进一步评估。WARN的低计算成本使其非常适合集成到可穿戴技术中,从而实现持续的心脏监测和早期房颤检测,这有可能减少紧急干预并改善患者预后。