Kurizky Patricia Shu, Martins Gladys Aires, Carneiro Jamille Nascimento, Gomes Ciro Martins, Mota Licia Maria Henrique da
Dermatology Service, Hospital das Forças Armadas, Brasília (DF), Brazil.
Dermatology Service, Hospital Universitário de Brasília, Universidade de Brasília, Brasília (DF), Brazil.
An Bras Dermatol. 2018 Nov/Dec;93(6):801-806. doi: 10.1590/abd1806-4841.20183071.
Psoriasis has a significant impact on quality of life (QoL). Sexual life can also be affected, with sexual dysfunction being reported by 25-70% of patients.
To determine the occurrence of sexual dysfunction and evaluate QoL in women with psoriasis.
This case-control study included women aged 18-69 years. The validated Brazilian Portuguese versions of the Female Sexual Function Index (FSFI) and of the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36) were administered to all participants to assess sexual function and QoL, respectively. Patients with psoriasis underwent clinical evaluation for the presence of comorbidities, especially psoriatic arthritis and other rheumatic manifestations. Location of lesions and the extent of skin involvement were also assessed.
The sample consisted of 150 women, 75 with diagnosis of psoriasis and 75 healthy controls. Prevalence of sexual dysfunction was high in women with psoriasis (58.6% of the sample). Prevalence was statistically higher in women with psoriasis than in controls (P = 0.014). The SF-36 domain scores were also lower in women with psoriasis, with role limitations due to physical health, limitations due to emotional problems, and mental health being the most affected domains.
Sample size was calculated to evaluate the association between the occurrence of sexual dysfunction and psoriasis, but it did not include the determination of the possible causes of this dysfunction.
QoL and sexual function were altered in women with psoriasis and should be taken into consideration when assessing disease severity.
银屑病对生活质量（QoL）有重大影响。性生活也可能受到影响，据报道25%-70%的患者存在性功能障碍。
确定银屑病女性性功能障碍的发生率并评估其生活质量。
本病例对照研究纳入了18-69岁的女性。向所有参与者发放经过验证的巴西葡萄牙语版女性性功能指数（FSFI）和医学结果研究36项简短健康调查（SF-36），分别评估性功能和生活质量。对银屑病患者进行合并症临床评估，尤其是银屑病关节炎和其他风湿表现。还评估了皮损部位和皮肤受累程度。
样本包括150名女性，75名诊断为银屑病，75名健康对照。银屑病女性性功能障碍患病率较高（占样本的58.6%）。银屑病女性的患病率在统计学上高于对照组（P = 0.014）。银屑病女性的SF-36领域得分也较低，其中因身体健康导致的角色限制、因情绪问题导致的限制以及心理健康是受影响最大的领域。
计算样本量是为了评估性功能障碍的发生与银屑病之间的关联，但未包括确定该功能障碍的可能原因。
银屑病女性的生活质量和性功能发生了改变，在评估疾病严重程度时应予以考虑。
