Foot Holly, Chan Amy Hai Yan, Horne Rob
School of Pharmacy, The University of Queensland, Brisbane, QLD, Australia.
School of Pharmacy, The University of Auckland, Auckland, New Zealand.
Front Pharmacol. 2024 Jun 28;15:1351851. doi: 10.3389/fphar.2024.1351851. eCollection 2024.
Despite anti-inflammatory reliever (AIR) therapy now being the preferred treatment choice across all severities of asthma, many patients are still "attached" to their short-acting beta-agonist (SABA) reliever, believing this to be the best way to control their asthma. To encourage individuals to switch to AIR, it is important to first identify the beliefs that patients hold about AIR.
The aim of this paper was to describe the initial development and validation of the BMQ-AIR, a six-item screening tool which assesses and identifies patients' treatment beliefs about switching to AIR therapy.
Statements were identified from the primary literature that assessed patients' perceptions of AIR therapy and adapted from the Beliefs about Medicines Questionnaire (BMQ). Internal reliability was examined using Cronbach's alpha coefficient. Construct validity was evaluated by comparing scores on BMQ-AIR with a validated measure of medication adherence and SABA beliefs.
A total of 446 participants completed the online survey. The BMQ-AIR contained two subscales with three items each. Both the Necessity and Concerns subscales demonstrated good internal reliability, with Cronbach's α-values of 0.70 and 0.69, respectively. Both subscales were negatively correlated with self-report inhaled corticosteroid adherence (Necessity: r = -0.28, < 0.0001; Concerns: r = -0.28, < 0.0001) and positively correlated with SRQ scores (Necessity: r = 0.51, < 0.0001; Concerns: r = 0.44, < 0.0001).
Preliminary findings indicate that BMQ-AIR demonstrates satisfactory reliability and validity. BMQ-AIR is a promising tool that may help tailor interventions to an individual's specific beliefs and barriers to switching to better support individuals in stopping SABA and initiating AIR therapy.
尽管抗炎缓解药物(AIR)疗法目前是各种严重程度哮喘的首选治疗方法,但许多患者仍“依赖”其短效β-激动剂(SABA)缓解药物,认为这是控制哮喘的最佳方法。为鼓励患者改用AIR,首先确定患者对AIR的看法非常重要。
本文旨在描述BMQ-AIR的初步开发和验证,这是一种六项筛查工具,用于评估和识别患者改用AIR疗法的治疗观念。
从评估患者对AIR疗法看法的主要文献中确定陈述,并改编自《药物信念问卷》(BMQ)。使用克朗巴赫α系数检验内部信度。通过比较BMQ-AIR得分与经过验证的药物依从性和SABA信念测量值来评估结构效度。
共有446名参与者完成了在线调查。BMQ-AIR包含两个分量表,每个分量表有三个项目。必要性和担忧分量表均显示出良好的内部信度,克朗巴赫α值分别为0.70和0.69。两个分量表均与自我报告的吸入性糖皮质激素依从性呈负相关(必要性:r = -0.28,<0.0001;担忧:r = -0.28,<0.0001),与SRQ得分呈正相关(必要性:r = 0.51,<0.0001;担忧:r = 0.44,<0.0001)。
初步研究结果表明,BMQ-AIR具有令人满意的信度和效度。BMQ-AIR是一种有前景的工具,可能有助于根据个体的特定信念和改用障碍来调整干预措施,以更好地支持个体停用SABA并开始AIR疗法。