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营养和运动干预措施改善肥胖和不同疾病实体女性的受孕率。

Nutritional and exercise interventions to improve conception in women suffering from obesity and distinct nosological entities.

机构信息

Diabetes and Obesity Unit, Athens Medical Center, Athens, Greece.

Endocrine Unit, Athens Medical Center, Athens, Greece.

出版信息

Front Endocrinol (Lausanne). 2024 Jun 28;15:1426542. doi: 10.3389/fendo.2024.1426542. eCollection 2024.

DOI:10.3389/fendo.2024.1426542
PMID:39006367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11239444/
Abstract

Infertility among women, particularly those living with obesity, presents a multifaceted challenge with implications for reproductive health worldwide. Lifestyle interventions, mainly focusing on weight loss, have emerged as promising strategies to improve fertility outcomes in this population. This review aims to explore the effectiveness of various lifestyle interventions, encompassing dietary modifications and exercise regimens, in enhancing fertility outcomes among women with obesity and associated conditions such as polycystic ovary syndrome, congenital adrenal hyperplasia, type 2 diabetes mellitus, premenopause, hypothyroidism and eating disorders. Methodology of study search encompass a broad spectrum, ranging from interventions targeting weight management through slow or rapid weight loss to dietary approaches emphasizing whole food groups, specific nutrients, and dietary patterns like low-carbohydrate or ketogenic diets, as well as the Mediterranean diet. By synthesizing existing findings and recommendations, this review contributes to the understanding of lifestyle interventions in addressing infertility, with an emphasis on the population of women of reproductive age with excess weight and known or unknown infertility issues, while promoting their integration into clinical practice to optimize reproductive health and overall well-being.

摘要

肥胖女性的不孕问题是一个多方面的挑战,对全球的生殖健康都有影响。生活方式干预主要侧重于减肥,已成为改善肥胖女性生育结局的有前途的策略。本综述旨在探讨各种生活方式干预措施,包括饮食改变和运动方案,在改善肥胖和相关疾病(如多囊卵巢综合征、先天性肾上腺皮质增生症、2 型糖尿病、绝经前、甲状腺功能减退症和饮食失调)的女性生育结局方面的有效性。研究搜索的方法包括广泛的范围,从针对体重管理的干预措施,通过缓慢或快速减肥,到强调全食物组、特定营养素和饮食模式(如低碳水化合物或生酮饮食)的饮食方法,以及地中海饮食。通过综合现有发现和建议,本综述有助于了解生活方式干预措施在解决不孕问题方面的作用,重点关注超重且存在已知或未知不孕问题的育龄女性人群,并促进将其纳入临床实践,以优化生殖健康和整体健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/11239444/27f31599a222/fendo-15-1426542-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/11239444/27f31599a222/fendo-15-1426542-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69f/11239444/27f31599a222/fendo-15-1426542-g001.jpg

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2
Low-Glycemic Load Diets and Thyroid Function: A Narrative Review and Future Perspectives.低血糖负荷饮食与甲状腺功能:叙述性综述及未来展望。
Nutrients. 2024 Jan 25;16(3):347. doi: 10.3390/nu16030347.
3
Ketogenic nutritional therapy (KeNuT)-a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)-diet therapies in endocrinology and metabolism.
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Metabolites. 2025 Jun 8;15(6):379. doi: 10.3390/metabo15060379.
4
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Front Cell Dev Biol. 2025 May 23;13:1582039. doi: 10.3389/fcell.2025.1582039. eCollection 2025.
5
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J Endocrinol Invest. 2024 Mar;47(3):487-500. doi: 10.1007/s40618-023-02258-2. Epub 2024 Jan 18.
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