Research Centre for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, Ferrara, Italy.
Operative Unit of Dentistry, AUSL of Ferrara, Ferrara, Italy.
Clin Oral Implants Res. 2024 Nov;35(11):1406-1417. doi: 10.1111/clr.14327. Epub 2024 Jul 15.
To evaluate the influence of patient and implant-related factors on the changes of marginal bone levels (MBL) at implants with a follow-up ≥5 years.
At baseline (within 6 months from prosthetic insertion) and long-term (≥5 years after implant placement) visits, interproximal (mesial and distal) MBL were radiographically evaluated. To analyze factors predicting MBL change, the site (either mesial or distal) showing the highest MBL change (hChMBL site) was identified for each implant. Multilevel regression models were built to explain MBL change as well as the probability for a bone loss ≥2 mm at long-term.
942 implants in 312 patients with a mean follow-up of 8.02 ± 2.5 years were analyzed. MBL change was significantly predicted by baseline MBL, oral bisphosphonate (BP) intake, history of periodontitis, diabetes, and super-hydrophilic implant surface. Higher risk for a bone loss ≥2 mm was observed in patients with history of periodontitis (OR = 9.52, 95% CI 0.72-3.79) and taking BP (OR = 6.84, 95% CI 0.21-3.63). Mandibular implants had higher odds for bone loss ≥2 mm compared to maxillary implants (OR = 3, 95% CI 0.39-1.87).
The findings of the present study contribute to the identification of specific clinical scenarios at higher risk for implant-supporting bone loss that need to be strictly monitored during maintenance.
评估患者和种植体相关因素对种植体边缘骨水平(MBL)变化的影响,随访时间≥5 年。
在基线(修复体插入后 6 个月内)和长期(植入后≥5 年)检查时,通过放射学评估近中(近中和远中)MBL。为了分析预测 MBL 变化的因素,确定每个种植体中显示最高 MBL 变化的部位(近中或远中)(hChMBL 部位)。建立多水平回归模型来解释 MBL 变化以及长期内发生骨损失≥2mm 的概率。
对 312 名患者的 942 个种植体进行了分析,平均随访 8.02±2.5 年。基线 MBL、口服双膦酸盐(BP)摄入、牙周病史、糖尿病和超亲水种植体表面显著预测 MBL 变化。患有牙周病史(OR=9.52,95%CI 0.72-3.79)和服用 BP(OR=6.84,95%CI 0.21-3.63)的患者发生骨损失≥2mm 的风险更高。与上颌种植体相比,下颌种植体发生骨损失≥2mm 的几率更高(OR=3,95%CI 0.39-1.87)。
本研究的结果有助于确定具有更高种植体支持骨丢失风险的特定临床情况,在维护期间需要对此进行严格监测。