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全膝关节置换术后患者功能“平台期”何时出现?一项队列研究。

When does patient function "Plateau" after total joint arthroplasty? A cohort study.

机构信息

Division of Trauma and Orthopaedic Surgery, Department of Surgery, University of Cambridge, Cambridge, UK.

Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON , Canada.

出版信息

Int Orthop. 2024 Sep;48(9):2283-2291. doi: 10.1007/s00264-024-06248-8. Epub 2024 Jul 15.

Abstract

PURPOSE

With over 100,000 procedures completed per year, hip and knee arthroplasty are two of the most common surgical procedures performed in Canada. There has been literature indicating that patient reported outcome measures (PROM) will start to plateau between six and 12 months. The purpose of this paper was to analyze the trajectory of PROMs following total hip and knee arthroplasty (THA and TKA), as well as assess the impact of any potential confounders on this trajectory. The central research question was: At what point do PROMS plateau among patients that undergo elective THA and TKA?

METHODS

This study was a retrospective analysis of data from a prospective database. Patients were eligible if they had undergone an elective, primary THA/TKA with Oxford Scores recorded pre-operatively, and at least at two of the following four time points: six weeks, six months, one year, and two years.

RESULTS

Mean pre-operative Oxford scores were 18.0 (7.8) for THA, and 20.1 (7.5) for TKA. For both THA and TKA, there were statistically significant interval improvements in Oxford scores from six weeks [THA: 33.8 (7.9)/TKA: 28.7 (7.8)] to six months [THA: 40.2 (7.3)/TKA: 35.9 (8.3)], and from six months to one year [THA: 41.0 (7.3)/TKA: 37.3 (8.4)], but not from one to two years [THA: 40.0 (8.5)/TKA: 36.4 (9.6)].

CONCLUSIONS

Patients undergoing either primary THA or TKA can expect clinically meaningful improvements in the first six months after surgery. Beyond this time point, there is a plateau in PROMs. These findings are important for both setting patient expectations in pre-operative discussions, and allowing surgeons to have a realistic understanding of their patients' expected post-operative course.

摘要

目的

每年完成超过 100,000 例手术,髋关节和膝关节置换术是加拿大最常见的两种手术。有文献表明,患者报告的结果测量(PROM)将在 6 至 12 个月之间开始趋于平稳。本文旨在分析全髋关节和膝关节置换术(THA 和 TKA)后 PROM 的轨迹,并评估任何潜在混杂因素对该轨迹的影响。核心研究问题是:接受选择性 THA 和 TKA 的患者的 PROMS 何时达到平台期?

方法

这是一项对前瞻性数据库中数据的回顾性分析。如果患者接受了择期、初次 THA/TKA,且术前记录了牛津评分,并至少在以下四个时间点中的两个时间点记录了评分,则患者符合入组条件:六周、六个月、一年和两年。

结果

THA 的平均术前牛津评分是 18.0(7.8),TKA 的平均术前牛津评分是 20.1(7.5)。对于 THA 和 TKA,从六周[THA:33.8(7.9)/TKA:28.7(7.8)]到六个月[THA:40.2(7.3)/TKA:35.9(8.3)],以及从六个月到一年[THA:41.0(7.3)/TKA:37.3(8.4)],患者的牛津评分均有统计学显著的间隔改善,但从一年到两年[THA:40.0(8.5)/TKA:36.4(9.6)],则没有统计学显著的间隔改善。

结论

接受初次 THA 或 TKA 的患者可以预期在手术后的前六个月内获得有临床意义的改善。在此时间点之后,PROM 达到平台期。这些发现对于术前讨论中设定患者预期以及让外科医生对患者术后预期过程有现实的理解都很重要。

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