Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, University of Bologna, Via Zamboni 33, Bologna, 40126, Italy.
Department of Geriatrics and Orthopaedics, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.
Cerebellum. 2024 Dec;23(6):2629-2637. doi: 10.1007/s12311-024-01721-x. Epub 2024 Jul 15.
The COVID-19 pandemic has brought attention to neurological complications, including cerebellitis, characterized by inflammation of the cerebellum. Despite its rare occurrence, cerebellitis has been associated with COVID-19 infection, albeit the pathogenic mechanisms remain unclear.
We present the case of a 22-year-old male with acute onset ataxia and dysarthria during a SARS-CoV-2 infection. Diagnostic evaluations ruled out other causes, confirming cerebellitis. Treatment included steroid therapy, vitamin supplementation, physiotherapy, and intravenous immunoglobulins. Rehabilitation focused on enhancing balance, coordination, and daily activities. The patient showed significant improvement in functional abilities, with increased autonomy in daily activities and improved ambulation. Despite persistent mild symptoms, the multidisciplinary rehabilitation approach led to remarkable progress.
This case underscores the importance of recognizing and managing neurological complications, such as cerebellitis, in COVID-19 patients. A comprehensive approach combining medical treatment and rehabilitation is essential for optimizing outcomes. Further research is needed to elucidate the pathogenesis and optimal management strategies for such complications.
COVID-19 大流行引起了人们对包括小脑炎在内的神经系统并发症的关注，小脑炎的特征是小脑炎症。尽管小脑炎很少见，但它与 COVID-19 感染有关，尽管其发病机制仍不清楚。
我们报告了一例 22 岁男性 SARS-CoV-2 感染后急性发作的共济失调和构音障碍。诊断评估排除了其他原因，确诊为小脑炎。治疗包括类固醇治疗、维生素补充、物理治疗和静脉注射免疫球蛋白。康复侧重于增强平衡、协调和日常活动能力。患者的功能能力显著改善，日常生活的自主性增加，行走能力改善。尽管仍有轻微症状，但多学科康复方法取得了显著进展。
本病例强调了在 COVID-19 患者中识别和管理神经系统并发症（如小脑炎）的重要性。结合医疗和康复的综合方法对于优化结果至关重要。需要进一步研究以阐明此类并发症的发病机制和最佳管理策略。
