Department of Life Sciences, Aberystwyth University, Aberystwyth, UK.
Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Adv Exp Med Biol. 2024;1454:507-539. doi: 10.1007/978-3-031-60121-7_13.
Trematode infections stand out as one of the frequently overlooked tropical diseases, despite their wide global prevalence and remarkable capacity to parasitize diverse host species and tissues. Furthermore, these parasites hold significant socio-economic, medical, veterinary and agricultural implications. Over the past decades, substantial strides have been taken to bridge the information gap concerning various "omic" tools, such as proteomics and genomics, in this field. In this edition of the book, we highlight recent progress in genomics and proteomics concerning trematodes with a particular focus on the advances made in the past 5 years. Additionally, we present insights into cutting-edge technologies employed in studying trematode biology and shed light on the available resources for exploring the molecular facets of this particular group of parasitic helminths.
吸虫感染是一种经常被忽视的热带病,尽管它们在全球范围内广泛流行,并具有寄生多种宿主物种和组织的显著能力。此外,这些寄生虫还具有重要的社会经济、医学、兽医和农业意义。在过去的几十年中,人们在利用各种“组学”工具(如蛋白质组学和基因组学)方面取得了重大进展,填补了这一领域的信息空白。在本书的这一版中,我们重点介绍了过去 5 年来在基因组学和蛋白质组学方面有关吸虫的最新进展,并深入探讨了用于研究吸虫生物学的尖端技术,以及探索这一特殊类群寄生虫分子特征的可用资源。