Department of Medicine, Division of Cardiovascular Medicine (Z.A., F.R., T.L.A.), Stanford University School of Medicine, CA.
Stanford Cardiovascular Institute (Z.A., F.R., T.L.A.), Stanford University School of Medicine, CA.
Circulation. 2024 Jul 16;150(3):171-173. doi: 10.1161/CIRCULATIONAHA.124.069680. Epub 2024 Jul 15.
Our research investigates the societal implications of access to glucagon-like peptide-1 (GLP-1) agonists, particularly in light of recent clinical trials demonstrating the efficacy of semaglutide in reducing cardiovascular mortality. A decade-long analysis of Google Trends indicates a significant increase in searches for GLP-1 agonists, primarily in North America. This trend contrasts with the global prevalence of obesity. Given the high cost of GLP-1 agonists, a critical question arises: Will this disparity in medication accessibility exacerbate the global health equity gap in obesity treatment? This viewpoint explores strategies to address the health equity gap exacerbated by this emerging medication. Because GLP-1 agonists hold the potential to become a cornerstone in obesity treatment, ensuring equitable access is a pressing public health concern.
我们的研究调查了胰高血糖素样肽-1(GLP-1)激动剂的获得对社会的影响,特别是鉴于最近的临床试验表明司美格鲁肽在降低心血管死亡率方面的疗效。对谷歌趋势的长达十年的分析表明,对 GLP-1 激动剂的搜索量显著增加,主要集中在北美。这一趋势与肥胖的全球流行率形成对比。鉴于 GLP-1 激动剂的高成本,一个关键问题出现了:这种药物获取方面的差异是否会加剧肥胖治疗方面的全球健康公平差距?这一观点探讨了应对这种新兴药物加剧的健康公平差距的策略。由于 GLP-1 激动剂有可能成为肥胖治疗的基石,确保公平获得是一个紧迫的公共卫生问题。