Ingram V M, Ogren M P, Chatot C L, Gossels J M, Owens B B
Proc Natl Acad Sci U S A. 1985 Oct;82(20):7131-5. doi: 10.1073/pnas.82.20.7131.
A monoclonal antibody (B1) produced against rat embryonic forebrain membranes shows specific and striking immunohistochemical staining of Purkinje cells in the monkey cerebellum in a pattern of broad parasagittal alternating bands of cells either possessing or lacking the B1 antigen. In addition, the neurons of the deep cerebellar nuclei and some neurons of the motor cortex and of the spinal cord also contain the B1 antigen. Neurons with the B1 antigen were also seen in the somatosensory cortex, the vestibular and cochlear nuclei, and the retina.
一种针对大鼠胚胎前脑细胞膜产生的单克隆抗体(B1),在猴小脑的浦肯野细胞中呈现出特异性且显著的免疫组织化学染色,形成了具有或缺乏B1抗原的细胞的宽矢状旁交替带模式。此外,小脑深部核团的神经元以及运动皮层和脊髓的一些神经元也含有B1抗原。在体感皮层、前庭和耳蜗核以及视网膜中也可见到具有B1抗原的神经元。